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Old 12-17-2021, 02:37 PM
 
761 posts, read 447,145 times
Reputation: 785

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113338/

Overdiagnosis and Overtreatment of Prostate Cancer

I realize this thread is not about overdiagnosis, but my question is: Why is overdiagnosis a problem if doctors are so reliable in giving the proper advice to their patients?

Read the patient summary at the end of the article.

This was only one link out of many found here: https://www.google.com/search?q=Over...hrome&ie=UTF-8

The following link calls overtreatment an epidemic:

https://www.cnn.com/2014/07/18/healt...ent/index.html
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Old 12-17-2021, 02:48 PM
 
Location: Forests of Maine
37,465 posts, read 61,396,384 times
Reputation: 30414
My urologist had to wait until he got the pathology report on the biopsy before he could say for sure if it was cancer. The pathology report stated the Gleason on the cancer.

I do not see where an overdiagnosis could happen when a tissue sample is analyzed in a lab.

Are there doctors somewhere who make claims of cancer without a biopsy?
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Old 12-18-2021, 09:37 AM
 
761 posts, read 447,145 times
Reputation: 785
Quote:
Originally Posted by Submariner View Post
My urologist had to wait until he got the pathology report on the biopsy before he could say for sure if it was cancer. The pathology report stated the Gleason on the cancer.

I do not see where an overdiagnosis could happen when a tissue sample is analyzed in a lab.

Are there doctors somewhere who make claims of cancer without a biopsy?
https://www.renalandurologynews.com/...0study%20finds.

Biopsy-gleason-scores are often wrong; see details by clicking the above link

"In 29% of cases, high biopsy scores are down graded to 7 or less after radical surgery, study finds."

Last edited by LongevitySeeker; 12-18-2021 at 09:45 AM..
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Old 12-18-2021, 09:55 AM
 
761 posts, read 447,145 times
Reputation: 785
https://pubmed.ncbi.nlm.nih.gov/26989367/

Conclusion of the above article: PSA can be an indicator for predicting the Gleason score.

The problem with that is the PSA test has a false positive rate of about 70%.

https://www.google.com/search?q=how+...ABCGAxCLAzIICA
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Old 12-18-2021, 10:26 AM
 
Location: Forests of Maine
37,465 posts, read 61,396,384 times
Reputation: 30414
Before hitting the paywall I was able to access a part of that article

Quote:
Nearly one third of prostate tumors judged to have high Gleason scores at biopsy may be intermediate-risk cancers,
It looks like they are saying that less than one-third of pathology reports claiming a high gleason, have turned out after surgery to be low gleason disease.

Still cancer, just a lower gleason.



In my understanding our culture has a big issue with lab techs. All lab techs. In any lab if you pay for a second lab tech to re-check the results you will find a third of the first lab techs to be in error.

This happens in Police Department forensic labs.

In the current plandemic, we have seen a lot of arguments about which style of lab testing should be used and news articles about false positives.

If you think back to the 1980s, To convict anyone of a crime for having THC in their urine, the courts decided that urinalysis must be done double-blind by three separate independent labs before you could send anyone to prison for THC in their urine.

Individual lab techs mis-read results in a third of all labs, every where.
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Old 12-18-2021, 10:35 AM
 
Location: Forests of Maine
37,465 posts, read 61,396,384 times
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PSA testing has NEVER been an indicator of cancer.

A PSA test tests for the presence of Prostate Specific Antigens. A high PSA test indicates that your prostate has some form of infection going on. Nobody should ever confuse an infection with cancer.

Anyone who tries to argue that PSA testing is not a good indicator of cancer, is trying to sell you an old nag.

You would do much better to examine the paint on your house to see if that paint is peeling, as an indication of whether you have brain cancer.
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Old 12-19-2021, 10:01 AM
 
761 posts, read 447,145 times
Reputation: 785
Quote:
Originally Posted by Submariner View Post
PSA testing has NEVER been an indicator of cancer.

A PSA test tests for the presence of Prostate Specific Antigens. A high PSA test indicates that your prostate has some form of infection going on. Nobody should ever confuse an infection with cancer.

Anyone who tries to argue that PSA testing is not a good indicator of cancer, is trying to sell you an old nag.

You would do much better to examine the paint on your house to see if that paint is peeling, as an indication of whether you have brain cancer.
https://www.mayoclinic.org/tests-pro...r%20in%20males.

"A PSA test is a blood test used primarily to screen for prostate cancer."

Getting a biopsy and a Gleason score depends on first getting a PSA test.

Last edited by LongevitySeeker; 12-19-2021 at 10:09 AM..
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Old 12-21-2021, 09:56 AM
 
761 posts, read 447,145 times
Reputation: 785
Quote:
Originally Posted by LongevitySeeker View Post
https://www.mayoclinic.org/tests-pro...r%20in%20males.

"A PSA test is a blood test used primarily to screen for prostate cancer."

Getting a biopsy and a Gleason score depends on first getting a PSA test.

It's just sad that the PSA test has a false positive rate of 70%.

I stopped getting tested 5 years ago at age 75.

https://www.google.com/search?q=at+w...AAQFhAeMgUIABC

The above link states: PSA testing is not recommended for men over the age of 70.
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Old 12-21-2021, 11:34 AM
 
Location: Forests of Maine
37,465 posts, read 61,396,384 times
Reputation: 30414
Quote:
Originally Posted by LongevitySeeker View Post
It's just sad that the PSA test has a false positive rate of 70%.
A PSA test DOES NOT test for cancer.

Anyone who tries to tell you that a PSA test is for cancer is lying to you.

A PSA test tests for the presence of Prostate Specific Antigens to indicate if you have an infection in your prostate.

It may be a bacterial infection.
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Old 02-22-2022, 03:00 PM
 
761 posts, read 447,145 times
Reputation: 785
Quote:
Originally Posted by Submariner View Post
A PSA test DOES NOT test for cancer.

Anyone who tries to tell you that a PSA test is for cancer is lying to you.

A PSA test tests for the presence of Prostate Specific Antigens to indicate if you have an infection in your prostate.

It may be a bacterial infection.
Something tells me you didn't read my link so here it is again:

https://www.mayoclinic.org/tests-pro...r%20in%20males

It says, "PSA is a protein produced by both cancerous and noncancerous tissue in the prostate...."

"....high levels of PSA may indicate the presence of prostate cancer. However, many other conditions, such as an enlarged or inflamed prostate, also can increase PSA levels.

The point I was trying to make in earlier posts is: There's no perfect test for prostate cancer.

The only other test available is the digital exam but that's not perfect either.

The problem is: You have to have some kind of test in order to justify getting a biopsy.
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