I really enjoy Grand Finale and Barresis. Here are the links:
The Grand Finale Restaurant - Cincinnati, Ohio
Barresi's Italian Restaurant // Home Page
For less expensive eats I'd recommend:
Blue Ash Chili - for double deckers
Graeters - for old-fashioned handmade ice cream
Village Kitchen on Wooster - it reminds me of my Grandma's cooking/kitchen
Rileys in Greenhills - nice family restaurant
Skyline Chili - great, but unusual, cheese coneys and three ways
Toots on Montgomery - a quirky place that serves fried pickles
Silver Wok on Kenwood - a seven table, family owned, Chinese joint
Echo on Edwards - no frills, just great food
Arthur's on Edwards - good food w/Graeter's right around the corner
I hope you get to sample some of these local favorites. Happy eating!