All of these suggestions are really good.
I would also add to keep an eye on the Detroit Shoreway area, including Gordon Square. Tons of redevelopment going on. You just need to follow Detroit going east towards downtown. You can find the websites here:
Detroit Shoreway and
Gordon Square Arts District
You can find...
Room Service, DuoHome and other cool shops/galleries
Luxe with great food and drinks
The Happy Dog for live music, drinks and fantastic Sunday brunch
The Capital Theatre is opening in October to show indie and foreign films
Cleveland Public Theatre for live productions
Don't be afraid to venture out a little to all the near west side has to offer.