Cmow
As a software engineer you husband should first submit resumes to Technology companies in the state.
These links may provide some information
You Belong in CT - Software IT
Computer Software Companies in Connecticut (CT)
Design Software Connecticut - Connecticut, design software, Connecticut software design, Connecticut graphic design, Connecticut web designDesign SoftwareSoftware Development
Senior Software Design Engineer - Wilton - Connecticut
If his specialty is Biotechnology- The New Haven area is perhaps a leader here for new companies in the genre. Stamford would have perhaps the largest number of jobs for software designers and engineers.
Hartford would have the fewest- but it would be best to check all the metro regions of the state. Hartford would by far have the lowest cost of living.
The SF Bay area is the national leader in technology- Silicon valley perhaps the most saturated region worldwide in the number of software and hardware companies it is home to. Connecticut's IT industry is far smaller.
I fully understand the cost of living in San Jose-Sunnyvale-Santa Clara can be daunting for many people. Connecticut is a high quality state, with much to offer- finding the appropriate employment will be the important factor for you as a first step in moving here. Best of luck.