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Old 08-10-2011, 12:17 PM
 
Location: Canada
3,164 posts, read 2,725,000 times
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My beagle will be 15 later this month. She was on Deramax for her arthritis but yesterday the vet gave me 50mg tablets tramadol to be taken every 12 hours. I woke up this morning to find a big puddle of pee by the door - and that was just after one tablet. All the same I gave her the next tablet around 11 and she's been drinking water excessively.

I was told about constipation and possible drowsiness until she gets used to the tramadol but I wasn't told about excessive thirst. Should I be worried? She isn't drowsy in the slightest. She doesn't look uncomfortable other than being thirsty. My vet told me not to skip a pill for at least a week and after that, depending on how she is doing I might be able to give her less of a dose.

I mean I am worried. I am always worried about her.

Last edited by netwit; 08-10-2011 at 12:18 PM.. Reason: typo
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Old 08-11-2011, 02:30 AM
 
Location: In the middle...
1,249 posts, read 1,224,295 times
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Talking Tramadol: Wikipedia...

Talking with your vet is always the best place to statt.

Tramadol may be used to treat post-operative, injury-related, and chronic (e.g., cancer-related) pain in dogs and cats[75] as well as rabbits, coatis, many small mammals including rats and flying squirrels, guinea pigs, ferrets, and raccoons. Tramadol comes in ampules in addition to the tablets, capsules, powder for reconstitution, and oral syrups and liquids; the fact that its characteristic taste is distasteful to dogs, but can be masked in food, makes for a means of administration. No data that would lead to a definitive determination of the efficacy and safety of tramadol in reptiles or amphibians is available at this time, and, following the pattern of all other drugs, it appears that tramadol can be used to relieve pain in marsupials such as North American opossums, Short-Tailed Opossums, sugar gliders, wallabies, and kangaroos among others.

Tramadol for animals is one of the most reliable and useful active principles available to veterinarians for treating animals in pain. It has a dual mode of action: mu agonism and mono-amine reuptake inhibition, which produces mild anti-anxiety results. Tramadol may be utilized for relieving pain in cats and dogs. This is an advantage because the use of some non-steroidal anti-inflammatory substances in these animals may be dangerous.

When animals are administered tramadol, adverse reactions can occur. The most common are constipation, upset stomach, decreased heart rate. In case of overdose, mental alteration, pinpoint pupils and seizures may appear. In such case, veterinarians should evaluate the correct treatment for these events. Some contraindications have been noted in treated animals taking certain other drugs. Tramadol should not be co-administered with selegiline or any other psychoactive class of medication such as selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, or monoamine oxidase inhibitors. In animals, tramadol is removed from the body via liver and kidney excretion. Animals suffering from diseases in these systems should be monitored by a veterinarian, as it may be necessary to adjust the dose.

Hope this helps!

Luv-A-Bull.Denver
"From wet noses to wiggly butts, out dogs are not just dogs, they are family!"
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Old 08-11-2011, 06:57 AM
 
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I have used Tramadol but don't recall a increase in thirst. I havent read anywhere where that is one of the side effects. I would call the vet and make sure nothing else is going on.
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Old 08-11-2011, 07:38 AM
 
Location: SE Michigan
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Have you called your vet yet?

Increased thirst and peeing can indicate kidney problems too, which would not be uncommon in a 15-year-old dog, especially one that's been taking NSAIDs. When did she last have a blood panel done?
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Old 08-11-2011, 07:48 PM
 
Location: Canada
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Thank you, all. I was busy with the farrier and didn't have a chance to post an update.

Yes, I called the vet yesterday and he told me that increased thirst was not a side effect of tramadol. It seems to have passed, whatever it was. Luba isn't drinking more than normal. She is not acting even slightly sedated, and in fact appears to be in more pain than usual from her arthritis. He took her off the Deramaxx completely, and told me to give the tramadol as indicated for at least a week for it to have the maximum effect.

He had also said that it was a very low dose and that I could give it 3 times a day. I have to go into town tomorrow and I'm going to ask him about it as I'm not sure whether I should wait the whole week on twice a day, or since she isn't acting drugged at all and is in obvious pain whether I should try increasing the dose to 3 X a day now.

A possible reason for her thirst is that she had a bout of diarrhea late last week. At first it seemed that it was only watery poop the one day, because the next day she had no accidents, and then two days after the original diarrhea, I woke up to some very unpleasant surprises in front of our doors and she really had the runs that day.

I fasted her for a day and then put her on boiled hamburger and rice and that resolved itself apparently. But I am leery about putting Metamucil into her regular food until I was sure her diarrhea was over. She now appears to be constipated (the tramadol). Anyway, that same day of the change to tramadol, she started drinking water like nobody's business, and I woke up to giant puddles in front of every door.

But since I posted, that too seems to have stopped. I did think of kidney problems but the vet said to just keep an eye out as to whether her excessive thirst worsened or continued and so far, knock on wood, it hasn't. Maybe she was drinking so much to make up for what fluids she lost during her bout with diarrhea?

I so do not want a dog funeral this year I worry about her.
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Old 08-17-2011, 04:46 PM
 
Location: Canada
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Just an update. Luba is dying. She is in kidney failure. The vet gave me something I am too tired to look up right now, something that coats her stomach as he said that it was possible she had tiny ulcers on her stomach lining. She was eating grass all the time. Whatever it was he gave her stopped the nausea, he also upped her tramadol to every eight hours, and aside from being weak and unable to walk more than a few steps, she seems comfortable, without being drowsy. Her appetite is still there.

At nearly 15 years old, there is nothing anyone can do. I know she has had a great life with me, with acres to roam, dog friends, and plenty of mice to catch and gophers to threaten. But I am still beyond sad.
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Old 08-17-2011, 04:52 PM
 
Location: SE Michigan
6,192 posts, read 7,145,189 times
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I am so sorry.

Fifteen is a very respectable age. Is the med Cerenia?
Give her lots and lots of hugs, remember she is living in the moment, as dogs do. It sounds like she had a wonderful life with you. It's a tough place to be, where you are now. ((hugs))
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Old 08-17-2011, 05:54 PM
 
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I am so sorry.
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Old 10-18-2012, 08:57 AM
 
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Your Luba helped my dog, Bob, today.
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Old 12-21-2012, 09:01 AM
 
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I am so sorry, I am reading your thread more than a year later. I can understand when you write I am always worried about her. I can relate perfectly, I have a terrier mixed breed named Candie, which we rescued from a neighbor. She has been with us for at least 13 years, which makes me think she could be 15 years or older because she had already had pups and was a young female when we took her. As a spirited terrier mix, she loved chasing iguanas, lizards and rodents. She was the most energetic dog you could imagine, jumping over fences when called and always begging for a slice of cheese. But just a week ago, she suddenly developed a head tilt with apparent pain as she would go through a seizure like fix where she yelped and screamed in apparent pain. That was gut wrenching to see and I could only use my vet as a confessionary as I was unconsolable. The doctor has prescribed a small cocktail of pills tramadol 50 mgs twice a day, gabapentin 50mgs, torbutrol 5 mg 1/2 twice a day, and prednisolone 20 mgs 1/2 twice a day. This may seem a lot but we tried several dosages and she continued in pain specially at night making me think that the effects of the drugs wore out at night. I gave her the first mix of these pills this morning and she seems to be sleepy and drowsy but at least her symptoms of pain are relieved. I gave her a bath and as I was finishing she began whining, seemingly under pain. So I dried her the best I could and let her be.

I write this as a Cathartic release, making no semantic or word edits as I want to openly express empathy to you and assure you I feel exactly the same way you did. Thank you for your love towards your beloved pet!
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