Poor Dr. Ayl he is such a nice guy yet his actual patients ( the dogs) all want to hide from him instead of being thankful that he has given them more time.
Oh to be snubbed by your "special projects"
I did opt to add the cytoxan to the piroxicam as part of Dash's antiangiogenic protocol. I had said I will not do chemo but I am willing to try this as this is considered to be a metronomic therapy rather then outright chemo.
Chemo involves large doses of the toxic drug given at once once a week or more or less frequent doses depending on the drug. To me that is like throwing a bomb in your house then waiting to see what remains. ( of both healthy cells and cancer cells) Usually the toll is alot of healthy cells destroyed and few cancer cells
With the metronomic therapy it is a very small dose of the cytoxan given every other day so is more like a snyper going in to shoot the bad guys. If I recall Dr. Ayl said he uses the small dose of cytoxan as an alkalizing agent
with the piroxicam so it is more of an antiangiogenic approach then a true chemo approach if I understand it correctly.
Dash has always had a cast iron gut as he has eaten things that would make a normal dog vomit or at least have bad diarrhea but he gets neither: like a whole cake he stole off the counter at my parent's house on thanksgiving when everyone went outside for awhile! He started counter surfing and stealing when he was put on the perscription food due to calcium oxalate stones. He has never had any bad side effects to antibiotics while Jazz gets major diarrhea with most of them. I am thinking he will do well with the cytoxan since it is a small dose and if not then we stop it. My only worry is it could irritate his bladder so I have to make sure he drinks alot to keep that bladder flushed which I try to do to prevent the stones too.
There is a 3rd drug that we could add later on it is a drug for diabetics and is on the expensive side according to Dr. Ayl so we will wait and see about that one.So for now we will try this approach as long as he tolerates it ok.
The hard part was finding the 25mg cytoxan pills as the pharmacies I called either have never carried it or said it has been discontinued. Costo has the generic so we are going with that. It is $25.00 for the months supply so not bad.Costso probably has the best prices anyway.
Sneezing is way down now as is the drainage
. Now that he is feeling better Jazz is back to keeping him out of the bedroom at night if he leaves he is not allowed back in! She is the queen and he has always listened to her
She is back to pushing him around which I take as a good sign as she had stopped doing that back when he started having problems.
I hope Tillie improves with the clavamox. Keep me posted.
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Dash loves to swim in pools and always jumps in at my dad's house.especially right before we leave so I have to drive home with a wet dog
