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Old 04-26-2022, 06:57 AM
 
11,610 posts, read 10,431,928 times
Reputation: 7217

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For those looking for a speculation, perhaps check out Omeros (OMER). Read the Q4 conference call transcript at Seeking Alpha (free registration required). After reaching an historical low last week, OMER popped yesterday, up 5 percent in a weak market.



Two significant catalysts for OMER price action are pending, both related to Narsoplimab, a monoclonal antibody that targets the lectin pathway. Read the Q4 earnings conference call transcript for a discussion of pending FDA approval of Narsoplimab as an orphan drug, and about the release of data on Narsoplimab's effectiveness as a treatment for COVID patients. The FDA approval of Narsoplimab was impaired when responsibility for Narsoplimab was reassigned to a different FDA division due to a reorganization.


I'm also intrigued by Omeros' anti-addiction drug.



https://www.omeros.com/pipeline/


Omeros is bouncing off a 52-week low and has a large short position (over 10 percent of shares outstanding). A year ago, OMER was trading above $18, so there likely is some tax loss selling to capture short-term losses, and many potential buyers on the sidelines due to the wash sale 30-day rule.
Positive news about Narsoplimab may power OMER much higher. It's possible that the market already has discounted negative news, given the stock's recent sell-off and the OMER pipeline.
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Old 04-26-2022, 05:49 PM
 
Location: Southeast US
8,609 posts, read 2,307,737 times
Reputation: 2114
I think there's an Investing subforum. This is the Economics subforum
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Old 04-27-2022, 01:15 PM
 
11,610 posts, read 10,431,928 times
Reputation: 7217
Quote:
Originally Posted by Eyebee Teepee View Post
I think there's an Investing subforum. This is the Economics subforum

Sorry, I meant to post it in the investing forum, explaining why I couldn't find the post when I just looked there. I will repost it in the investing forum.


As a side note, however, I will say that one reason for our inflation is the devastating, and inexcusably inadequately examined impact of COVID on the American work force. The impact has several components:


1) Deaths of members of the work force.


2) Work force members disabled by long COVID and no longer able to work.



3) Lower productivity of workers suffering from long COVID symptoms.


4) Persons fleeing certain jobs such as medical care (including nurses and doctors) due to the COVID risk, and the demonstrated indifference of our politicians, especially anti-maskers and anti-vaxxers, to the risks of treating COVID patients. Compared to Asian nations, including democracies such as Australia, New Zealand and Japan, we've had relatively poor levels of public health measures such as contract tracing, mandatory and enforced quarantines of those infected or exposed, local lockdowns, mandatory masking, and vaccine incentives such as severe restrictions on those who refuse vaccinations. We've had low rates of masking and vaccination compared to these nations. Note that much of Australia had no COVID spread in half of its population and very low relative rates of death, hospitalization and likely long COVID until December of 2021, when restrictions were relaxed due to very high relative rates of vaccination, because Australian federal and state governments didn't understand until it was too late that three doses of vaccination were needed to protect against the highly contagious Omicron variant. See post 8 in this thread for a short discussion of how the Australian economy fared versus the U.S. economy during the pandemic.


http://www.city-data.com/forum/flori...l#post63252906


5) Withdrawal from the work force of persons no longer willing to deal with the public and be exposed to COVID, especially more vulnerable elderly and immunocompromised workers.



6) Decline in our educational standards and delay of graduates entering the work force.


7) Significant rise in medical insurance costs as a result of COVID, which raises labor costs.


This all is in addition to the money spent by governments, especially federal stimulus funds, to keep the economy from collapsing during the pandemic. BTW, hundreds of billions of these stimulus funds were stolen, apparently often by foreign actors, including Russians, due to governmental incompetence.



IF Narsoplimab is able, as indicated by studies, to protect endothelial cells from damage during COVID infections, and prevent clotting, including microclots, it may be another tool in reducing the ongoing negative impact of the COVID epidemic on the American economy. Such a successful drug won't repair the damage already inflicted on the American economy.


https://news.tulane.edu/pr/tulane-re...scular-effects



Pfizer's Paxlovid antiviral pill will have a similar beneficial impact of muting the economic impact of the COVID epidemic on the American economy, but infected individuals must be promptly tested and administered the drug, a process unlikely to occur in the large percentage of Americans who view COVID as a hoax or relatively harmless.


https://www.reuters.com/world/us/us-...on-2022-04-26/

Last edited by WRnative; 04-27-2022 at 02:18 PM..
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Old 05-02-2022, 07:24 PM
 
Location: New York Area
35,061 posts, read 16,995,362 times
Reputation: 30204
Quote:
Originally Posted by WRnative View Post
4) Persons fleeing certain jobs such as medical care (including nurses and doctors) due to the COVID risk, and the demonstrated indifference of our politicians, especially anti-maskers and anti-vaxxers, to the risks of treating COVID patients. Compared to Asian nations, including democracies such as Australia, New Zealand and Japan, we've had relatively poor levels of public health measures such as contract tracing, mandatory and enforced quarantines of those infected or exposed, local lockdowns, mandatory masking, and vaccine incentives such as severe restrictions on those who refuse vaccinations. We've had low rates of masking and vaccination compared to these nations. Note that much of Australia had no COVID spread in half of its population and very low relative rates of death, hospitalization and likely long COVID until December of 2021, when restrictions were relaxed due to very high relative rates of vaccination, because Australian federal and state governments didn't understand until it was too late that three doses of vaccination were needed to protect against the highly contagious Omicron variant. See post 8 in this thread for a short discussion of how the Australian economy fared versus the U.S. economy during the pandemic.
How about something far more obvious; that Obamacare and the insurance companies have taken a lot of the profit away from the practice of medicine, and shifted it to the practice management groups?
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