Originally Posted by hueyeats
Be ready for your kitty to be "sick" as they will throw up... its their nature.
Don't feed them for 4 hrs before your set-off time and if you can, make a long stop for an overnight stay (feed & water for the cat(s) at night but not 4 hrs before travel) at a pet friendly motel (like Redroof).
I was told to feed them the night before, make sure the tummy is empty. The really FUN part was finding where she hid, though a trailing leash was helpful. And getting the pill IN the cat when she figured out why I was trying to catch her.
Don't assume silence is 'fine' if you don't medicate. My girl didn't make a sound. I discovered she didn't since she was just to scared to. Sedating her made it easier on her.