Cleanest City: In Pictures: America's 10 Cleanest Cities - Forbes.com
Overall (both the ones that made the top 100 are in the Orlando Metro, not all States have a single city on the top 100 let alone 2. You can check previous years to see Orlando consistently has cities in the cut): Best Places to Live 2009 - States: Florida - from MONEY Magazine
UCF was ranked the 5th best up-and-coming University (it is also now the nation's 3rd largest University by enrollment)
Best Colleges - Education - US News and World Report
You are right Florida as a whole is bad in Foreclosures...
The Top 25 Foreclosure Cities - The Home Front (usnews.com)
However of the worst it is the only one with every single city showing marked improvements. Not to mention the obvious benefits for first time buyers in today's market.
While Orlando didn't make the cut in top 25, Jacksonville, Miami, and Tampa all did for best places to buy Real-Estate in 2010. Miami and Tampa are both making improvements as indicated by the top 25 foreclosure page, I have to believe Orlando isn't too far behind
In Depth: Best Cities To Buy A Home - 1. Denver, Colo. - Forbes.com
Orlando came in at #37 on the list of Best Cities for Young Professionals
In Depth: Best Cities For Young Professionals - Forbes.com
As for Unemployment Orlando is far from the best but we're far from the worst as well 288/372 metros. (Higher number is worse) That means there are almost 100 metros worse off than Orlando.
Unemployment Rates for Metropolitan Areas
Ranked as High Sufficiency by the GaWC for importance on the global scale
GaWC - The World According to GaWC 2008
Of course ranked in the top for Tourism
Top 25 Most Visited Tourist Destinations in America | The Travelers Zone
There's no real list but Florida is about to be what many consider the first states with Highspeed Rail and the first Phase includes Orlando (as does the second, and third). Some consider it the second in US. Either way if there was a list, we'd be in either #1 or #2
Let us not forget the long overdue SunRail | Changing the Way Central Florida Travels
that is accompanying it. Far from the first Lightrail, and long overdue, but still long before most MSA have a lightrail system.