I have relatives in Colquitt county and Moultrie, that is SW Georgia. Valdosta is about an hour's drive. The previous poster summed it up well. It is very rural: people are generally friendly but you do have a small town mentality to deal with (assuming you have lived in smaller towns). Housing near or in Valdosta and Tifton may be your best bet. Most of your shopping can be done in those "larger sized" SW GA towns.
One very beautiful city in that area is Thomasville which is a comfortable drive from Valdosta but seems more inconvenient for Berrien County. Thomasville has many beautiful old homes and is worth at least a drive through. Thomasville used to the last train stop for passenger service many years ago, so many wealthy people bought retirement homes there long before Florida became popular.
Since are concerned about schools, definitely check out the counties in that area with this website (Georgia Public Policy Foundation) (it covers all of Georgia, and is a must for people with kids and deciding on a decent public school) You can narrow down your search by the rankings of all public schools relative to that area.
Georgia Public Policy Foundation - www.gppf.org
Good luck!