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Old 04-14-2011, 10:35 PM
 
Location: Boise
2,684 posts, read 6,052,529 times
Reputation: 991

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So my grandmother has a prescription for oxymorphone for pain, and one 20 mg pill is too strong. She cannot get a hold of her doctor for a couple days and doesn't have internet and wanted to know if it is safe to cut one in half to take. So I am finding out for her. She is worried that because part of the pill will be exposed without the time-release coating covering it, she will get too much of the drug at a time. Is it safe for her to take a half of the pill?
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Old 04-14-2011, 11:55 PM
 
Location: Mostly in my head
19,631 posts, read 53,468,042 times
Reputation: 18533
I don't think so but call her pharmacist in the a.m. and ask them.
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Old 04-15-2011, 06:41 AM
 
1,610 posts, read 3,839,293 times
Reputation: 693
Call 3 different druggist and get an opinion.I doubt that a medical expert is on this forum.JMHO
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Old 04-15-2011, 12:03 PM
 
Location: In a house
13,258 posts, read 34,604,245 times
Reputation: 20198
It is generally -not- safe to split time-release pills.

Opana ER isn't a time release though. It's an extended-release. It means it's probably enteric-coated, and will take longer to dissolve and absorb into the blood stream, and will be effective for longer as well. 10mg is the lowest dose of Opana ER; regular Opana is available in 5 and 10mg.

What you might want to -consider- doing, is split the ER into quarters, and let her try one quarter of a tablet. The worst thing that can happen, in that case, is it'll dissolve at a faster pace than the ER, but she'll only get around 5mg worth of drug in her bloodstream, which is around the same as she'd get by taking an intact full-strength 20mg ER tablet, unsplit.

At best, it'll solve the problem.
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Old 04-15-2011, 02:29 PM
 
42 posts, read 73,446 times
Reputation: 55
Quote:
Originally Posted by jufrbo View Post
So my grandmother has a prescription for oxymorphone for pain, and one 20 mg pill is too strong. She cannot get a hold of her doctor for a couple days and doesn't have internet and wanted to know if it is safe to cut one in half to take. So I am finding out for her. She is worried that because part of the pill will be exposed without the time-release coating covering it, she will get too much of the drug at a time. Is it safe for her to take a half of the pill?
Call the pharmacy. Any pharmacy. They will be able to tell you.
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Old 04-15-2011, 02:30 PM
 
42 posts, read 73,446 times
Reputation: 55
Time released pills should not be cut in half. That will allow the entire dose of med to be dumped into your grandmother's system all at once instead of being released gradually.
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Old 04-15-2011, 03:58 PM
 
Location: In a house
13,258 posts, read 34,604,245 times
Reputation: 20198
Except oxymorphone doesn't come in time release capsules. It comes in extended release tablets.
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Old 04-15-2011, 09:03 PM
 
Location: Destrehan, Louisiana
2,192 posts, read 6,033,749 times
Reputation: 3600
Quote:
Originally Posted by SouthernBelleInUtah View Post
I don't think so but call her pharmacist in the a.m. and ask them.
Here is the best advice

busta
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Old 04-16-2011, 10:09 PM
 
Location: Native Floridian, USA
4,896 posts, read 5,863,520 times
Reputation: 6050
Quote:
Originally Posted by AnonChick View Post
It is generally -not- safe to split time-release pills.

Opana ER isn't a time release though. It's an extended-release. It means it's probably enteric-coated, and will take longer to dissolve and absorb into the blood stream, and will be effective for longer as well. 10mg is the lowest dose of Opana ER; regular Opana is available in 5 and 10mg.

What you might want to -consider- doing, is split the ER into quarters, and let her try one quarter of a tablet. The worst thing that can happen, in that case, is it'll dissolve at a faster pace than the ER, but she'll only get around 5mg worth of drug in her bloodstream, which is around the same as she'd get by taking an intact full-strength 20mg ER tablet, unsplit.

At best, it'll solve the problem.
excellent advice and I also had realized the difference between time released and extended release.... thx for common sense info..
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Old 04-17-2011, 03:01 PM
 
Location: Northern NH
4,551 posts, read 9,859,296 times
Reputation: 3782
Quote:
Originally Posted by DarwinFan View Post
Time released pills should not be cut in half. That will allow the entire dose of med to be dumped into your grandmother's system all at once instead of being released gradually.

Don't ever split or cut a time release tablet. It could be very dangerous just like this poster stated.
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