Obese people who had more of the enzyme in their livers and fat tissue had more inflammation and were more likely to be diabetic than obese people with little of the enzyme in their tissues. Experiments with mice confirm the finding and suggest that inhibiting the enzyme might promote better health in obese people.
https://www.sciencenews.org/blog/sci...ealthy-obesity
Journal article:
http://dx.doi.org/10.1016/j.cell.2014.04.043