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Old 03-07-2018, 11:43 AM
 
17,952 posts, read 5,798,779 times
Reputation: 12158

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Quote:
Originally Posted by NorthofHere View Post
The best way to fight dementia of the aging variety (Alzheimer's and other types of dementia may be hereditary) is by exercising the body and the mind. Be careful of supplements because if we eat right we really don't need them unless we have a deficiency like Vitamin B12. Overtaking certain supplements can cause more harm than good and some supplements interact badly with medications you may be on.
I agree with you to a big point re: exercise etc BUT many older folks with joint issues etc have a hard time with exercise, many are happy to be walking. I know a LOT of older people who play bridge and it's amazing for the brain/memory. I take supps that help with overall circulation including the brain to the toes. My joint issues with advanced OA have stopped me from major moving. Long story there.

With aging comes deficiencies. If only our foods did it all and many older folks again don't eat well, many have to cook for themselves and can't do it like they did all their lives. I know a lot of older people.
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Old 03-07-2018, 03:48 PM
 
465 posts, read 212,026 times
Reputation: 1170
Quote:
Originally Posted by jaminhealth View Post
All this chemistry is way over my head but is it basically saying how important cholesterol is. I've been taking COQ10 as part of my heart health regime for some time. Is it not necessary? Thanks.
No, CoQ10 is important to supplement if you are older, and ESPECIALLY if you're on statins. I was just saying that it doesn't solve ALL of the problems associated with statins.

I don't even understand the full HMG-CoA pathway. But there are many products in between HMG CoA and cholesterol, so you're messing with all of those. There are more direct ways to block cholesterol, if it truly is a problem.
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Old 03-10-2018, 11:04 AM
 
2,895 posts, read 827,529 times
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Quote:
Originally Posted by Haksel257 View Post
To the people that suggest taking CoQ10 (yet another cost) will alleviate all negative side-effects, what about prenylation?

Here are the things that you are inhibiting, way before HMG-CoA gets made into cholesterol: https://upload.wikimedia.org/wikiped...se_pathway.svg

That's completely ignoring the downstream products of cholesterol, which are both numerous and absolutely vital.

My point is, you're inhibiting a very important pathway high up in the chain, with a million downstream products, in a LARGE segment of an unhealthy population. All based on the poor assumption that high cholesterol is THE CAUSATIVE factor in heart disease. That bothers me, and I can see why some people feel the dire need to inform the uninformed.

Do doctors really check anything else related to the HMG-CoA reductase pathway? Or do they only see high cholesterol and prescribe a generic statin?

And yeah, 15 threads might be overkill XD
YES!! It is a DIRE NEED, people should be informed!

There is so much arrogance in our medical industry. Assuming they understand things better than nature does. They can mess with vital processes that are MUCH too complicated to fully understand.
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Old 03-14-2018, 11:58 PM
 
Location: Georgia, USA
21,215 posts, read 25,701,268 times
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Originally Posted by Good4Nothin View Post
There is so much arrogance in our medical industry. Assuming they understand things better than nature does. They can mess with vital processes that are MUCH too complicated to fully understand.
Just because you do not understand those "vital processes" does not mean there are no experts that do, right down to the molecular level and the genetics for more and more of it.

How does "nature" understand anything?
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