Welcome to City-Data.com Forum!
U.S. CitiesCity-Data Forum Index
Go Back   City-Data Forum > General Forums > Health and Wellness
 [Register]
Please register to participate in our discussions with 2 million other members - it's free and quick! Some forums can only be seen by registered members. After you create your account, you'll be able to customize options and access all our 15,000 new posts/day with fewer ads.
View detailed profile (Advanced) or search
site with Google Custom Search

Search Forums  (Advanced)
 
Old 01-04-2019, 09:58 AM
 
Location: deafened by howls of 'racism!!!'
52,293 posts, read 34,040,569 times
Reputation: 29036

Advertisements

can't wait to see some human trials results.

New Compound Shows Promise in Treatment of Alzheimer’s

paper here

Quote:
Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer’s and even restores memories in mice,*they report Jan. 2 in the journal Cell Reports.
The binding of amyloid beta peptides to prion proteins triggers a cascade of devasting events in the progression of Alzheimer’s—accumulation of plaques, a destructive immune system response, and damage to synapses.

Strittmatter and research scientist*Erik Gunther*screened tens of thousands of compounds looking for molecules that might interfere with the damaging prion protein interaction with amyloid beta. They found that an old antibiotic looked like a promising candidate but was only active after decomposing to form a polymer. Related small polymers retained the benefit and also managed to pass through the blood-brain barrier.
They then dissolved the optimized polymeric compound and fed it to mice engineered to have a condition that mimics Alzheimer’s. They found that synapses in the brains were repaired and mice recovered lost memory.
Reply With Quote Quick reply to this message

 
Old 01-04-2019, 02:28 PM
 
6,288 posts, read 2,836,188 times
Reputation: 7207
Lots of things work in mice but not people. There's an old drug called clioquinol that gets rid of plaques in mice, but the tests in people were not conclusive.



https://www.newscientist.com/article...e-brain-cells/
Reply With Quote Quick reply to this message
 
Old 01-04-2019, 07:37 PM
 
Location: Southern California
29,267 posts, read 16,606,435 times
Reputation: 18902
There are supplements right now that reduce amyloid plaque, I take one for many yrs.
Reply With Quote Quick reply to this message
 
Old 01-04-2019, 07:46 PM
 
Location: Central IL
20,726 posts, read 16,237,058 times
Reputation: 50368
Quote:
Originally Posted by jaminhealth View Post
There are supplements right now that reduce amyloid plaque, I take one for many yrs.
Share, share!
Reply With Quote Quick reply to this message
 
Old 01-04-2019, 08:46 PM
 
6,288 posts, read 2,836,188 times
Reputation: 7207
Quote:
Originally Posted by jaminhealth View Post
There are supplements right now that reduce amyloid plaque, I take one for many yrs.
I have not heard that. Inflammation plays a part in Alzheimer's so anti-inflammatories may help. I take turmeric and fish oil.

Here's a good article:
https://www.gmjournal.co.uk/can-diet...disease-part-1
Reply With Quote Quick reply to this message
 
Old 01-04-2019, 09:13 PM
 
Location: Southern California
29,267 posts, read 16,606,435 times
Reputation: 18902
Quote:
Originally Posted by reneeh63 View Post
Share, share!
If it's good enough for Mice, why not Man?

https://link.springer.com/article/10...640-009-9000-x

There are many more links to read also on this Grape and the brain.
Reply With Quote Quick reply to this message
 
Old 01-04-2019, 09:49 PM
 
6,288 posts, read 2,836,188 times
Reputation: 7207
Quote:
Originally Posted by jaminhealth View Post
If it's good enough for Mice, why not Man?

https://link.springer.com/article/10...640-009-9000-x

There are many more links to read also on this Grape and the brain.
https://www.npr.org/sections/health-...ried-in-people
Quote:
Rats and humans have been on their own evolutionary paths for tens of millions of years. We've developed our own unique features, and so have the rodents.
Reply With Quote Quick reply to this message
Please register to post and access all features of our very popular forum. It is free and quick. Over $68,000 in prizes has already been given out to active posters on our forum. Additional giveaways are planned.

Detailed information about all U.S. cities, counties, and zip codes on our site: City-data.com.


Reply
Please update this thread with any new information or opinions. This open thread is still read by thousands of people, so we encourage all additional points of view.

Quick Reply
Message:

Over $104,000 in prizes was already given out to active posters on our forum and additional giveaways are planned!

Go Back   City-Data Forum > General Forums > Health and Wellness

All times are GMT -6.

© 2005-2024, Advameg, Inc. · Please obey Forum Rules · Terms of Use and Privacy Policy · Bug Bounty

City-Data.com - Contact Us - Archive 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37 - Top