Like much of the M4 corridor, Reading is overpiced suburban dullsville. At least commuting in reverse you would avoid the herd charging into London every day.
Looking on
www.rightmove.co.uk studios near Paddington station cost from £170 pw, compared with £70 pw in Reading. Plus commuting is not cheap.
Depending how well paid the job is, and how much you want to immerse yourself in London culture, it might be better to be based in Reading and travel in once or twice a week for the nightlife.