Hey there, we live on the other side of the bay in Spanish Fort so I have some info for you about the area. We've been here about 3 years and moved here from Atlanta. I'de be glad to answer any questions for you.
I can only offer what I've learned driving around and shopping and doing activities in the area, I don't have old school knowledge that many others can offer, but I'll share what I've got
Unfortunately I don't have a ton of info about the neighborhoods over there as I live on the other side of the bay. It generally takes me about 30 minutes(middle of the day) to get over to W Mobile near the airport. There are some new shopping areas going in, Kohl's, Super Target, Sonny's & Chilis. There is a movie theater and several strip malls that are newer in that area of Schillinger/Airport Road. Then you have the older ones on the next block like Hobby Lobby/Walmart(trashy)/Kmart, etc. That intersection is very congested.
I do everything with my 2 younger kids and my opinion on crime is that you can pretty much know where to go and not go if you know what I mean. I've never seen anything or had problems personally.
The area of Mobile is pretty dull as far as family activities, my biggest complain, no outdoor activites except festivals. You have to make your own schedule here, things just don't jump out at you.
As far as traffic goes, yes Airport Blvd is congested, a very busy street with a lot of traffic lights. You do have a good mall there at I-65/Airport so that causes a lot of congestion.
If it's possible I would recommend the Spring Hill area of Mobile or moving across the bay to Daphne/Spanish Fort. The majority of people we meet in Mobile want to move over here. The schools are great in my area, but I don't have info about Mobile except there are a lot of private schools. I don't care too much for most of the people I meet in Mobile, a lot of them just don't take care of themselves as much as I am used to coming from ATL where everyone is business minded and working.
Good luck, I am sure if she speaks to people at USA that they can advise her on where to live that has a decent commute.
Biloxi is probably 45 minutes from Mobile if you like to go to casinos, it's fun.