We went this past July to New Orleans with our French exchange student.
I don't think there will be much of translation for museums. There may be some on
tours but you would have to book ahead of time.
We didn't find much even in French for him. And we needed it because his English was terrible. You will be able to find guidebooks in different languages, but I can't remember where I found our French one.
I know there is a small book shop across from the Wyndham Bourbon Orleans, on that street right behind the Cathedral.
The French Quarter is in great shape and so is the Garden District /Uptown area. My husband is a project manager and had lots of work there on national chains he was overseeing- we were over there a lot. An easy example of Southern plantations is Destrehan Plantation, about 30 minutes or less to the north of the city.
Don't be surprised if they are the most interested in shopping! They can buy so much over here because of the good Euro! My mom has friends from her Italy days who visit ,and the highlight (for them) is shopping at the outlet malls and eating in our chain restaurants.

They just don't care about the museums, we found. But maybe we just had 5 couples who were shopaholics!