Former Mass-hole here

We chose the Charlotte area and have no regrets. Here are a few things that come to mind...
The weather here is waaay bettah!

You still get all 4 seasons but a much shorter winter. Hardly any snow unless you live in the higher elevations. I also feel it is a great place to raise a family. It just seems more family oriented here and I enjoy living in a subdivision and knowing who all my neighbors are.
Car insurance (at least mine) is half of what I paid in Mass. Housing is of course more affordable. The pace here is slower and I find people are friendlier, even the transplants. There are lots of restaurants and shopping around and everything seems so clean and new, especially compared to Boston.
The sales tax here is higher than MA. And as you probably know the unemployment rate is high here right now.
I can't comment on Raleigh but there is a thread I saw comparing Raleigh to Charlotte and if you search other threads I think you'll find a lot of opinions and some useful info. Of course the best thing to do is take a trip and explore it for yourself!