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View Poll Results: Are we getting ripped off with health care system?
Yes, it's time for reform 21 87.50%
No, I love to pay $100 for a bottle of medicine 3 12.50%
Voters: 24. You may not vote on this poll

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Old 12-18-2009, 11:20 AM
 
10,719 posts, read 20,289,211 times
Reputation: 10021

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The drug companies spend billions on research and development. It's extremely expensive to engineer, produce and test drugs. There are so many phases of drug testing that take years and money. And even after all this time and money, if the drug fails to be safe in clinical trials, it's over! Imagine spending a billion dollars to produce a drug and then have it not work out. Let me give you an example, Phizer spent hundreds of millions of dollars creating the drug torcetrapib. This drug was unique in that elevates HDL significantly which is another strategy lower one's risk of coronary artery disease. The current cholesterol lowering drugs focus on lowering LDL. However, one's risk for CAD is considerably reduced if a patient is able to elevate their HDL over 60. It had a lot of promise and many people were anticipating the arrival of this drug. Unfortunately, it failed clinical trials.

How does this related to this topic? Well drug companies spend billions producing drugs only for some hack in a third world country or a socialized country to pirate and exploit the research the drug company spent a lot of money producing themselves. That's how these countries are able to offer prescriptions for such a cheap price...they didn't produce it!

One more thing...ever wonder why more cancer drugs and other unique medication aside from cholesterol and pain medications aren't being made...the reason is because the government stopped paying for those drugs so the pharmaceutical industry stopped making drugs that people could use and instead put their efforts on making another statin and viagra to make money. You can thank the government for that. We can waste 100 billion dollars per year in Afghanistan but we can't pay for medications that people need.
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Old 12-18-2009, 11:23 AM
 
Location: London, U.K.
3,006 posts, read 3,869,127 times
Reputation: 1750
Quote:
Originally Posted by azriverfan. View Post
The drug companies spend billions on research and development. It's extremely expensive to engineer, produce and test drugs. There are so many phases of drug testing that take years and money. And even after all this time and money, if the drug fails to be safe in clinical trials, it's over! Imagine spending a billion dollars to produce a drug and then have it not work out. Let me give you an example, Phizer spent hundreds of millions of dollars creating the drug torcetrapib. This drug was unique in that elevates HDL significantly which is another strategy lower one's risk of coronary artery disease. The current cholesterol lowering drugs focus on lowering LDL. However, one's risk for CAD is considerably reduced if a patient is able to elevate their HDL over 60. It had a lot of promise and many people were anticipating the arrival of this drug. Unfortunately, it failed clinical trials.

How does this related to this topic? Well drug companies spend billions producing drugs only for some hack in a third world country or a socialized country to pirate and exploit the research the drug company spent a lot of money producing themselves. That's how these countries are able to offer prescriptions for such a cheap price...they didn't produce it!
You know that primary research is mainly paid for by taxes, and that drugs companies spend (if I remember correctly) 10 times more on marketing and advertising than R & D?
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Old 12-18-2009, 11:24 AM
 
Location: Reading, PA
4,011 posts, read 4,424,163 times
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The part that really is unconscionable is that some of that money being paid by the pharmaceutical companies for sales and marketing is done to pimp drugs for unapproved indications and/or for unapproved populations. Even when they are fined for their behavior, their profits for that illegal and immoral activity far exceeds the penalties.
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Old 12-18-2009, 11:27 AM
 
10,719 posts, read 20,289,211 times
Reputation: 10021
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Originally Posted by archineer View Post
You know that primary research is mainly paid for by taxes, and that drugs companies spend (if I remember correctly) 10 times more on marketing and advertising than R & D?
That isn't true. And to add to my point, I only referenced drugs that were successful, the vast majority of the medication they attempt to produce never pass clinical trials.
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Old 12-18-2009, 11:29 AM
 
Location: Tyler, TX
23,856 posts, read 24,091,732 times
Reputation: 15123
Quote:
Originally Posted by archineer View Post
You know that primary research is mainly paid for by taxes, and that drugs companies spend (if I remember correctly) 10 times more on marketing and advertising than R & D?
I'd really like to see the source of this information.
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Old 12-18-2009, 11:30 AM
 
10,719 posts, read 20,289,211 times
Reputation: 10021
Quote:
Originally Posted by Sagran View Post
The part that really is unconscionable is that some of that money being paid by the pharmaceutical companies for sales and marketing is done to pimp drugs for unapproved indications and/or for unapproved populations. Even when they are fined for their behavior, their profits for that illegal and immoral activity far exceeds the penalties.
Provide an example. Viagra was an antihypertensive that had certain positive side effects and was then prescribed for erectile dysfunction.
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Old 12-18-2009, 11:32 AM
 
10,719 posts, read 20,289,211 times
Reputation: 10021
Quote:
Originally Posted by swagger View Post
I'd really like to see the source of this information.
Don't bother, it doesn't exist. He will just provide some X-Files or some random website from a conspiracy theorist who makes all these unsubstantiated claims. That's why I simply said it isn't true because anyone who is educated on this topic knows that isn't true.
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Old 12-18-2009, 11:38 AM
 
8,629 posts, read 9,130,021 times
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Quote:
Originally Posted by Quick Enough View Post
If you don't like the cost of a drug, be brave, do without it. Quit whinning. I get tired of hearing all the "for profit" whinning. Do any of you work for free? Things cost money. Do you have any idea how much r&d costs? How long it takes to get a new drug on the market do to the FDA? If you want socialist benefits, move to a socialist country and quit trying to ruin this country.
You have absolutely know clue at all. But one day you will.
As stated earlier Pharma charges what they want period, because they can in the states, let me restate that "The Can". Most meds are marked up hundreds of thousands of a percent for each pill manufactured and there is a website that will calculate these for your for each med. Pharma companies can't get away with this in many modern countries because they are negotiated with, the US pays full retail price in most cases.
There are 3 meds I pay out of pocket for my wife who has a chronic condition at a hefty price of $800 per month. These are not rare drugs but common well advertised drugs.
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Old 12-18-2009, 11:45 AM
 
Location: Reading, PA
4,011 posts, read 4,424,163 times
Reputation: 843
Quote:
Originally Posted by azriverfan. View Post
Provide an example. Viagra was an antihypertensive that had certain positive side effects and was then prescribed for erectile dysfunction.
An example of what I was referring to -- the pimping of drugs for unapproved indications and unapproved populations? Easy.

Neurontin -- Pfizer to Pay $430 Million Fine over Illegal Marketing : NPR

The manufacturer is still at it: What Changes? Pfizer Fudged Neurontin Studies // Pharmalot

Geodon, Bextra, Zyvox, Lyrica: FDA: Pfizer ignored warnings, gets record fine | Philadelphia Inquirer | 09/03/2009 (http://www.philly.com/philly/business/homepage/20090903_FDA__Pfizer_ignored_warnings__gets_record _fine.html - broken link)
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Old 12-18-2009, 11:46 AM
 
13,648 posts, read 20,767,629 times
Reputation: 7650
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Originally Posted by archineer View Post
You know that primary research is mainly paid for by taxes, and that drugs companies spend (if I remember correctly) 10 times more on marketing and advertising than R & D?
Bunch of nonsense.

I have worked in Big Pharma (please put the tar & feathers away) and saw it all from the inside. Big Pharma is neither a charity nor a ward of the government.

If it was simply a matter of the government subsidizing all primary research for pharmaceuticals, then France, Sweden or some other nation would dominate the industry rather than the US.

As was said, it is very expensive to develop a drug. Think of like a compact disk. A pill, like a CD, is cheap enough to manufacture- that is the actual physical result. But the band that recorded the CD needed hours of rehearsal time, music lessons, studio time, equipment, paid engineers, etc, etc.

Likewise a drug results from years and years of research, testing, clearing bureacratic hurdles, and yes marketing and distribution. Scientists and doctors do not work for free- Do You? If the producer of a product, any product, cannot recoup the costs and make a profit, then they are not going to produce anything.
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