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07-08-2009, 02:49 PM
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80's Rebel
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Join Date: Dec 2006
9,779 posts, read 7,216,272 times
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First Drug Shown To Extend Life Span In Mammals
I was just reading on MIT Technology Review about how scientists at 3 different research centers in the USA have for the first time extended the life span of mammals by giving them the antifungal drug Rapamycin. Before this the only way to extend the life span was either by genetic engineering or calorie restriction. Also the scientists were amazed that this worked when administered to the mammals when they were already old and not just when they were young.
Will we ever pass the 120 year barrier ??
Technology Review Magazine - First Drug Shown to Extend Life Span in Mammals
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07-09-2009, 08:18 AM
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Bees? Not in Maine
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Join Date: Feb 2007
Location: Argyle, Maine
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neat

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07-09-2009, 09:05 AM
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Senior Member
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Join Date: Mar 2009
Location: Home
1,415 posts, read 354,552 times
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Quote:
Originally Posted by forest beekeeper
neat

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Why did I just picture the Addams Family?
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07-09-2009, 09:34 AM
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Senior Member
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Join Date: May 2007
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I'm just thankful that this isn't another "Marijuana the wonder drug" thread. 
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07-09-2009, 09:46 AM
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Bees? Not in Maine
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Join Date: Feb 2007
Location: Argyle, Maine
11,383 posts, read 6,247,618 times
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Quote:
Originally Posted by Ninjahedge
Why did I just picture the Addams Family?
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Did we all snap our fingers?
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07-09-2009, 09:54 AM
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m. Sons of the Republic of Texas
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Join Date: Jan 2008
Location: Juan Seguin, Texas
2,542 posts, read 1,648,240 times
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And then you have this: Obama's Health Zar says that any one over
61 years old that can not recover and contribute to the economy should not receive health care!! Well, guess what yawl, most of usare in that over 61 group!! Heaven help us if we get appendacidas (?)
or a blocked artery!!
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07-09-2009, 10:10 AM
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Bees? Not in Maine
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Join Date: Feb 2007
Location: Argyle, Maine
11,383 posts, read 6,247,618 times
Reputation: 2756
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Quote:
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Originally Posted by gy2020
And then you have this: Obama's Health Zar says that any one over 61 years old that can not recover and contribute to the economy should not receive health care!! Well, guess what yawl, most of usare in that over 61 group!! Heaven help us if we get appendacidas (?) or a blocked artery!!
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A lot of folks have been screaming for us to follow the European example of healthcare.
The future value of your life is weighed, and your treatment protocol is set according to that value.
If you are an Aristocrat, then you can recieve full care for a long time.
Otherwise once you turn 60 you can only get 'care and comfort', no life-saving efforts are allowed.
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07-09-2009, 01:02 PM
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Senior Member
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Join Date: Mar 2009
Location: Home
1,415 posts, read 354,552 times
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Quote:
Originally Posted by forest beekeeper
Did we all snap our fingers?
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Nah, but the next wort I thought of was:
"Sweet"
As for the drug, I wonder what is causing this longevity. Could it be preserving the DNA of the subject from life threatening mutation? Or maybe it just makes it less vulnerable to low-level degenerative diseases that never really register as life threatening to us since they never cause any outright symptoms or noticible signs.....
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07-09-2009, 02:50 PM
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Senior Member
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Join Date: Jun 2008
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It's going to require some further study to see exactly what it is about the antifungal that contributed to extending the lifespan of the mice. It wasn't clear if the antifungal was given to the mice once, or administered routinely over a longer period of time.
If I understand correctly, the extension in comparison to humans at age 60 would be roughly an additional 5.4 to 7.8 years. It's unknown if it would work with humans. If it does, there's still a downside: although it may have a life-extending potential, the antifungal suppresses the immune system making you more susceptable to loads of problems like being unable to fight off infections, which would seem might negate the life extention. In other words, in the end, there might be few if any years extended.
However, it may be possible to identify the specific properties in the antifungal that causes the extension and might be able to figure out a way of adding even more years. It's interesting.
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07-09-2009, 02:55 PM
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Senior Member
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Join Date: Jun 2008
1,080 posts, read 512,034 times
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Quote:
Originally Posted by gy2020
And then you have this: Obama's Health Zar says that any one over
61 years old that can not recover and contribute to the economy should not receive health care!! Well, guess what yawl, most of usare in that over 61 group!! Heaven help us if we get appendacidas (?)
or a blocked artery!!
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What's next? Anyone over 61 would be eligible to be shipped off to the nearest Soylent Green Factory? 
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