I'm going to second Greenville, but also recommend the Greenwood area. There are a lot of motorcycle enthusiasts in the area and plenty of non-congested roads to ride them on. We've got plenty of curves, straights, hills, and flats, and we're central to Greenville, Columbia, and Augusta without being so close to any of them that we are encumbered by their congestion. Greenwood is definitely a more country vibe, a lot more laid back, and a whole lot friendlier than some of the nearby bigger areas.
As far as hospitals go, Self Regional is a good one, too. My family has had good experiences with the healthcare system in general, though none of us have been in the actual hospital here, so my judgement is based on experience with affiliated doctors and word of mouth.
Home | Welcome to Self Regional Healthcare | Greenwood, SC
That said, when I elected to have surgery earlier this year, I went to St Francis Bon Secours in Greenville and chose a Greenville based surgeon due largely in part on the recommendation of my SIL who is an OR nurse there.
Greenville | Bon Secours St. Francis Health System
Hope that helps