You may want to check the distance learning courses. USD is headquarters for the state's distance learning program and you may want to check the website and your options. You may want to check
USD - Continuing Education to see what your options are with distance education. Also there is a higher education center in Rapid City called Higher Education Center West River that has an associates in Nursing, the website is
USD - USD Programs at HEC-WR. In the eastern part of the state, University of South Dakota (USD) and South Dakota State University both have nursing programs. The SDSU nursing program is probably the better of the two (a four year program) and I had some high school classmates who took their generals at USD and transferred up to SDSU to take nursing. SDSU also has a distance learning site that is located at
Degree Programs. I hope that this helps.