There really isn't a one size fits all for any areas or even street by street. You've got to check out the street signs where you are parking. For the most part, parking is open on weekends and holidays, but there are a lot of loading zones in the buisiness areas that you are talking about where parking isn't allowed on Sat mornings. On the flip side, there are areas that you can only park on Sundays (created for church parking). During the week, some parking restrictions end at 6:30, some end at 8:30. You also have sides of streets that restrict parking during rush hour. Also, watch for street cleaning restrictions.
I know it doesn't really help, but there really isn't an answer to your question.