Simpleguy,
First, my sympathy for you and yours.
Where are you moving from and what area will you be working?
All in all driving around Martinsburg is not bad. It has turned into a full bedroom community for DC workers.
Buying a home in Berkeley? I would suggest that you receive a full "certified" inspection of your home before you sign on the dotted line and that from an inspector who is registered professionally and possibly from Hagerstown or Winchester.
For schools, look to Hedgesville High or Mussleman. Martinsburg High has became rather bad.
Locations: If in town limits. Look to the west of Tennessee Avenue. Martinsburg's east side from the 700 block of West King to Burke and Green Hill has become very dicey. Downtown is old with little pride to turn it into the jewel it should be. Finding the Martinsburg Police precint is easy on Queen, just look for the porn shop and the police is right across the street
If looking into the North County side (Falling Waters) or the South (Bunker Hill) attempt to find a location with public utilities. Since there is no zoning and lack of other requirements you may find a .25 acre lot complete with well and septic. Well + Septic + small lots = Possibility of muddy poopy water.
Was born and raised in the B'urg and back due to elderly family members multiple times per year. The old place has changed over the years.
Good Luck