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I think what will eventually come out of all of the Genome research is that even if we have mutated Genes we can still express our Epigenome in a positive way to overide those bad Genes in many diseases especially Cancer.
Thank you for contacting Cancer Research UK about the article you read on the BBC news website. The research was actually carried out by scientists in America, at Washington University. Over this side of the pond, Cancer Research UK is funding a great deal of research into uncovering the genes that are involved in cancer, although we cannot afford to do the kind of analysis that has been undertaken by the US team in this particular case. You can read about some of this work on our website: Cancer Research UK : Finding cancer genes
We do know that inheriting faulty genes can increase the risk of cancer - such as faults in the BRCA1 or BRCA2 genes that increase the risk of breast cancer, or faults in the APC gene that increase the risk of bowel cancer. In some cases, we see families with a strong history of the same type of cancer, which suggests that there is a firm genetic link. We think these strong faults account for around one in twenty cancers.
There is more information about genes and cancer on our website : Cancer Research UK : Genes and cancer although this is quite technical.
However, cancer is a very common disease, affecting one in three people in the UK. So if a close relative develops cancer, it does not necessarily mean that it runs in the family, and it is difficult to comment more fully on your friend's situation. If he is concerned, I suggest he contacts our Cancer Information nurses: http://www.cancerhelp.org.uk/feedback.asp or talks to his GP.
Thank you for contacting us.
PHILADELPHIA (Nov. 13, 2008) — A small, antibody-like molecule created by researchers at Fox Chase Cancer Center can successfully attack two separate molecules on the surface of cancer cells at the same time, halting the growth of breast cancer cells in laboratory tests
Thought this was interesting as researches at the University of Texas Anderson Cancer Center have found that a protein PEA-15 tells cancer cells to eat themselves or autophagy by the cellular lysosomes especially in ovarian cancer. So women who produce this protein naturally stand a better chance of either not getting it to surviving it after diagnosis.
Hmm.....what about fasting or low carb diets like atkins as these also cause autophagy to happen in the cells.
Thought this was interesting as researches at the University of Texas Anderson Cancer Center have found that a protein PEA-15 tells cancer cells to eat themselves or autophagy by the cellular lysosomes especially in ovarian cancer. So women who produce this protein naturally stand a better chance of either not getting it to surviving it after diagnosis.
Hmm.....what about fasting or low carb diets like atkins as these also cause autophagy to happen in the cells.
Yeah. It would be interesting to see if something similar could work in other kinds of cancer.
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