If you're looking for remains of the aristocratic Antebellum South, then the biggest concentration is in Georgia east of the Ocmulgee River and north of the Altamaha River, specifically in and near an area bounded by Athens, Macon, Augusta and Savannah. In fact, the U.S. 129/U.S. 441 corridor from Macon/Milledgeville to Athens is called the "Antebellum Trail," where Georgia still has most of its Antebellum architecture and culture intact. The cities and towns they highlight along the route are Macon, Gray, Milledgeville, Eatonton, Madison, Watkinsville and Athens.
You can also find some Antebellum remains in cities and towns like Lexington, Washington, Lincolnton, Greensboro, Crawfordville, Warrenton, Thomson, Harlem, Monticello, Sparta, Wrens, Sandersville, Louisville, Waynesboro, Wrightsville, Wadley, Millen, Sylvania, Swainsboro, Statesboro, Springfield, Jeffersonville, Dublin, Soperton, Metter and Bloomingdale.
The highways that serve these cities and towns include the following U.S. highways:
U.S. 1 (Swainsboro, Wadley, Louisville, Wrens, Augusta)
U.S. 25 (Statesboro, Millen, Waynesboro, Augusta)
U.S. 78 (Athens, Lexington, Washington, Thomson, Harlem, Augusta)
U.S. 80 (Macon, Jeffersonville, Dublin, Swainsboro, Statesboro, Bloomingdale, Savannah)
U.S. 221 (Soperton, Louisville, Wrens, Harlem)
U.S. 278 (Madison, Greensboro, Crawfordville, Warrenton, Thomson, Harlem, Augusta)
U.S. 301 (Statesboro, Sylvania)
U.S. 319 (Dublin, Wrightsville, Wadley)
U.S. 378 (Washington, Lincolnton)
They also include the following state highways:
GA 11 (Macon, Gray, Monticello)
GA 15 (Soperton, Wrightsville, Sandersville, Sparta, Greensboro, Watkinsville, Athens)
GA 16 (Monticello, Eatonton, Sparta, Warrenton)
GA 17 (Bloomingdale, Millen, Louisville, Wrens, Thomson, Washington)
GA 18 (Gray, Jeffersonville)
GA 21 (Savannah, Springfield Sylvania, Millen)
GA 22 (Macon, Gray, Milledgeville, Sparta, Crawfordville, Lexington)
GA 24 (Milledgeville, Sandersville, Louisville, Waynesboro, Statesboro)
GA 44 (Eatonton, Greensboro, Washington)
GA 46 (Soperton, Metter)
GA 49 (Macon, Milledgeville)
GA 56 (Soperton, Swainsboro, Waynesboro, Augusta)
GA 57 (Macon, Wrightsville, Swainsboro)
GA 80 (Warrenton, Wrens, Waynesboro)
GA 83 (Monticello, Madison)
GA 88 (Sandersville, Wrens, Augusta)
But if you don't have time to take any of those highways, stick to the U.S. 129/U.S. 441 corridor from Macon/Milledgeville to Athens.