Quote:
Originally Posted by BikesareBetter
Its Windows, all programs in general 
Not at work..Home PC
What can I do to fix this problem or run programs?
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If all programs do not run, there may be something wrong with the PC or the operating system.
How old is the PC?
What is the configuration? RAM, HD space, Processor speed?
What version of Windows?
Have you tried "right click", "Open program"?
Easier solution would be to uninstall a specific program, restarting the system and reinstalling it.
Next solution would be to back up ALL DATA (to include email, photos, documents, bookmarks, tax information, whatever) and doing an Operating system reinstall/repair. If you don't feel comfortable with any of those steps, you should take it to a repair shop.