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A unique, lightweight, and easy to use anti-virus solution from the reputable Panda Security company. If your current anti-virus program is causing your computer's performance to dip, try this for size. Cloud Antivirus works on the concept of "cloud computing" and as such aims to do much of its processing "in the cloud" (that's via remote servers rather than your computer).
Spyware Terminator and Security Essentials should be enough already, as the former provides anti-spyware protection and the latter largely anti-virus protection.
However, I don't forsee any clashes if you use all four as both Panda Cloud and Immunet are cloud-based services that do not use up much resources on the client end. However, be prepared for increased network utilization, which may be a problem if you're not on an unlimited data plan.
Using all four together may not be a problem, but do you really need that? The key to security is not the size of your security arsenal, but common sense. As long as you pay attention to what you click, what you download, which site you visit, you should be fine..........