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Old 01-01-2021, 08:29 PM
 
Location: Land of the Free
6,741 posts, read 6,730,607 times
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Quote:
Originally Posted by ddeemo View Post
Your list appears to be incomplete because even if remove SPACs the list should be larger - there were 104 SPACs officially as of Oct, I doubt it is almost 3x larger now to get to your "approx 200 IPOs ex-SPACs".
167 SPACs went public along with 99 ETFs. These don't represent operating companies and should not be included.

A SPAC should be included only when it buys an operating company.
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Old 01-02-2021, 01:00 AM
 
Location: Land of the Free
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Quote:
Originally Posted by Avondalist View Post
Red vs blue factors into this because red states are more friendly to industry, both regulation wise and wage wise. Because investors just aren't investing in physical plants as much as they used to, red states get short shrift.
This is an interesting point. However, biomanufacturing is largely staying in blue states near the HQ's of the companies developing the drugs. Massachusetts and California are both strong here. The plants are so capital-intensive, and the process so delicate, there's a reluctance to put the factories too far from the top execs. Genentech, for example, has a huge manufacturing facility in Vacaville, CA, about an hour from its HQ and halfway to Sacramento. More companies are doing the same in that town. Similarly, COVID vaccine manufacturer Moderna, based in Cambridge, but with a large manufacturing facility not far away in Norwood, Mass.

Semiconductors have been like this their entire existence. You don't get large manufacturing moving out of the HQ metro with a lot of management and office employees going with it. Seen this in Austin, Portland, and Phoenix. Don't get big chip fabs in Alabama or South Carolina where you do get large auto and aviation plants. Outside of Austin and Raleigh-Durham, red states seem to do best in very mature industries.
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Old 01-02-2021, 02:31 AM
 
Location: Silicon Valley
7,650 posts, read 4,597,880 times
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Quote:
Originally Posted by TheseGoTo11 View Post
This is an interesting point. However, biomanufacturing is largely staying in blue states near the HQ's of the companies developing the drugs. Massachusetts and California are both strong here. The plants are so capital-intensive, and the process so delicate, there's a reluctance to put the factories too far from the top execs. Genentech, for example, has a huge manufacturing facility in Vacaville, CA, about an hour from its HQ and halfway to Sacramento. More companies are doing the same in that town. Similarly, COVID vaccine manufacturer Moderna, based in Cambridge, but with a large manufacturing facility not far away in Norwood, Mass.

Semiconductors have been like this their entire existence. You don't get large manufacturing moving out of the HQ metro with a lot of management and office employees going with it. Seen this in Austin, Portland, and Phoenix. Don't get big chip fabs in Alabama or South Carolina where you do get large auto and aviation plants. Outside of Austin and Raleigh-Durham, red states seem to do best in very mature industries.

Fabless Semi has beaten Fabrication. The winner is Taiwan...and it's very much concentrated there. The design is still in the US....for now.
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Old 01-02-2021, 04:50 AM
 
19,793 posts, read 18,079,394 times
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Quote:
Originally Posted by TheseGoTo11 View Post
This is an interesting point. However, biomanufacturing is largely staying in blue states near the HQ's of the companies developing the drugs. Massachusetts and California are both strong here. The plants are so capital-intensive, and the process so delicate, there's a reluctance to put the factories too far from the top execs. Genentech, for example, has a huge manufacturing facility in Vacaville, CA, about an hour from its HQ and halfway to Sacramento. More companies are doing the same in that town. Similarly, COVID vaccine manufacturer Moderna, based in Cambridge, but with a large manufacturing facility not far away in Norwood, Mass.

Semiconductors have been like this their entire existence. You don't get large manufacturing moving out of the HQ metro with a lot of management and office employees going with it. Seen this in Austin, Portland, and Phoenix. Don't get big chip fabs in Alabama or South Carolina where you do get large auto and aviation plants. Outside of Austin and Raleigh-Durham, red states seem to do best in very mature industries.



TI has been making digital and complex/high value analog circuits in Dallas and all-around the area for decades. There are several others as well.


You are trying really hard to paint a clear picture of something fuzzy in efforts to fit your political logic.
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Old 01-02-2021, 10:47 AM
 
Location: Indianapolis, East Side
3,070 posts, read 2,400,022 times
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Quote:
Originally Posted by TheseGoTo11 View Post
This is an interesting point. However, biomanufacturing is largely staying in blue states near the HQ's of the companies developing the drugs. Massachusetts and California are both strong here. The plants are so capital-intensive, and the process so delicate, there's a reluctance to put the factories too far from the top execs. Genentech, for example, has a huge manufacturing facility in Vacaville, CA, about an hour from its HQ and halfway to Sacramento. More companies are doing the same in that town. Similarly, COVID vaccine manufacturer Moderna, based in Cambridge, but with a large manufacturing facility not far away in Norwood, Mass.
Drugs are manufactured all over. Most of Pfizer's manufacturing sites are in the South and the Midwest. Roche has locations all over the world, including R&D in Indianapolis and Tucson. Novo Nordisk has an R&D center in Indy and Eli Lilly is based here.

People have also had to innovate just to become a desirable place to do business. You can't just hand out tax breaks--highly qualified people want a nice place to live and raise their families. Indiana, for instance, became a right-to-work state only rather recently. At a local level, Indianapolis has had to deal with the loss of tens of thousands of manufacturing jobs over the decades, several thousand abandoned houses (which deteriorate rapidly in a wet climate, attract vagrants, develop mold, and catch fire in many cases), abandoned factories and warehouses, environmental contamination, flight to the suburbs, high crime, and a reputation as a dull place. It took some innovation to create solutions, and get them passed, to turn some of those problems around--just not the kind of innovation that ends up as a public company.
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Old 01-02-2021, 11:09 AM
 
12,022 posts, read 11,572,686 times
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Silicon Valley, New York City, Boston, and LA are where most of the startups originate. Those cities are where the most highly sough after universities in finance and technology are clustered. Each has at least two or more that one would consider a private or public Ivy with business schools and engineering schools highly ranked. The professors and the recent graduates are often the founders and principals in the companies. You see it also in the coding boot camps which funnel graduates to mainly those cities to feed the startups with cheap software talent.

The migration of some industry out of California occurs periodically, usually late in the cycle because of the highs costs and the limits to growth in the Bay Area with deserts and mountains to the east and the ocean to the west. The commuting is really bad with the sprawl, although it would take me longer to drive the same distance in NYC or DC metro areas. Companies will look to move and take advantage of the tax inducements where they get 5- or 10-years free tax abatement on real estate or employee taxes.
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Old 01-02-2021, 01:14 PM
 
Location: Land of the Free
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Quote:
Originally Posted by sheerbliss View Post
Not biologics/large molecule drugs. You're giving a lot of examples from small molecule/pills, which are far more mature and growing far more slowly than large molecules. Major clusters for biomanufacturing are Vacaville, CA, north county San Diego, 128-495 corridor in Mass, RTP in North Carolina. Metro Portland is one of the fastest emerging markets.

Fill/finish, i.e. the packaging, is a little more spread out, but the challenging scale up and purification processes are in the regions I listed above.
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Old 01-02-2021, 01:19 PM
 
Location: Land of the Free
6,741 posts, read 6,730,607 times
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Quote:
Originally Posted by EDS_ View Post
You are trying really hard to paint a clear picture of something fuzzy in efforts to fit your political logic.
Economics is not about my feelings or yours, but looks like you're trying to make it about that.

Yes, blue states have a serious problem retaining auto and aviation jobs, the growth of the I-20 corridor in the South, Boeing in North Charleston, SC, and Airbus in Mobile, AL reflect that. Right-to-work laws and business friendly state government are almost essential now to bring in mature manufacturing industries.

But at the same time, innovative, groundbreaking companies are still mostly in blue states. These are all facts that have nothing to do with left/right politics. The left doesn't like how successful right-to-work has been and the right doesn't like how little VC is raised in red states. It's not that fuzzy in either case if you look at relocations and venture funded-new company formation.
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Old 01-02-2021, 02:18 PM
 
19,793 posts, read 18,079,394 times
Reputation: 17279
Quote:
Originally Posted by TheseGoTo11 View Post
Economics is not about my feelings or yours, but looks like you're trying to make it about that.

Yes, blue states have a serious problem retaining auto and aviation jobs, the growth of the I-20 corridor in the South, Boeing in North Charleston, SC, and Airbus in Mobile, AL reflect that. Right-to-work laws and business friendly state government are almost essential now to bring in mature manufacturing industries.

But at the same time, innovative, groundbreaking companies are still mostly in blue states. These are all facts that have nothing to do with left/right politics. The left doesn't like how successful right-to-work has been and the right doesn't like how little VC is raised in red states. It's not that fuzzy in either case if you look at relocations and venture funded-new company formation.
I'm an economist and see straight through what you are selling.
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Old 01-02-2021, 04:40 PM
 
Location: Land of the Free
6,741 posts, read 6,730,607 times
Reputation: 7588
Quote:
Originally Posted by EDS_ View Post
I'm an economist and see straight through what you are selling.
LOL, if you were any good as one you would debate the content, not make emotional comments like that.
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