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ISH is a condition whereby the systolic pressure (top no,) is significantly higher than what is desirable, and the diastolic pressure (bottom no.) is lower than avg., e.g., 170/70. Some writers have argued that ISH in the elderly is even more serious than overall high blood pressure, e.g., 170/100.
Anyway my numbers the past two yrs. have averaged upper 150s over 60s. The prescribed treatment regimen was bystolic which is a new type of beta blocker along with lisinopril, an ACE inhibitor. This course hasn't worked so well and in addition I have developed hyponatremia (low blood sodium).
Because one of lisinopril's side effects for some people is low blood sodium, the provider replaced it with losartan, an angiotensin receptor blocker. So now I still have ISH and low sodium, in addition to high serum potassium! One of losartan's side effects is high potassium for a surprising no. of patients.
I want to dump the regimen altogether and try another mode of treatment but the provider is dragging her heels. Some literature suggests that amlodipine, a calcium channel blocker, is effective against ISH and I haven't read anything about it messing up electrolytes.