Quote:
Originally Posted by Willamette City
What kind of nasal spray are you referring to? I use a saline spray. It seems pretty benign.
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I was going to ask and answer the same.
Regarding the ones with pharmaceutical chemicals, it is
clearly stated on the labels not to use for more than three days (usually), after which recommending seeing a doctor and warning of detrimental affects due to long-term use. So don't do it.
As for Flonase:
Flonase (fluticasone propionate nasal spray) drug
DESCRIPTION
The active component of FLONASE Nasal Spray is fluticasone propionate, a corticosteroid having the chemical name S-(fluoromethyl) 6α,9-difluoro-11β,17-dihydroxy-16α-methyl-3oxoandrosta-1,4-diene-17β-carbothioate, 17-propionate and the following chemical structure:
FLONASE (fluticasone propionate) Structural Formula Illustration
Fluticasone propionate is a white powder with a molecular weight of 500.6, and the empirical formula is C25H31F3O5S. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.
FLONASE Nasal Spray, 50 mcg is an aqueous suspension of microfine fluticasone propionate for topical administration to the nasal mucosa by means of a metering, atomizing spray pump. FLONASE Nasal Spray also contains microcrystalline cellulose and carboxymethylcellulose sodium, dextrose, 0.02% w/w benzalkonium chloride, polysorbate 80, and 0.25% w/w phenylethyl alcohol, and has a pH between 5 and 7.
After initial priming, each actuation delivers 50 mcg of fluticasone propionate in 100 mg of formulation through the nasal adapter.
Indications & Dosage
INDICATIONS
FLONASE® Nasal Spray is indicated for the management of the nasal symptoms of
perennial nonallergic rhinitis in adult and pediatric patients aged 4 years and older.
DOSAGE AND ADMINISTRATION
Administer FLONASE Nasal Spray by the intranasal route only. Prime FLONASE Nasal Spray before using for the first time or after a period of non-use (1 week or more) by shaking the contents well and releasing 6 sprays into the air away from the face. Shake FLONASE Nasal Spray gently before each use.
Patients should use FLONASE Nasal Spray at regular intervals since its effectiveness depends on its regular use. Maximum effect may take several days and individual patients will experience a variable time to onset and different degree of symptom relief.
Adults
The recommended starting dosage in adults is 2 sprays (50 mcg of fluticasone propionate each) in each nostril once daily (total daily dose, 200 mcg). The same total daily dose, 1 spray in each nostril administered twice daily (e.g., 8 a.m. and 8 p.m.) is also effective
. After the first few days, patients may be able to reduce their dose to 1 spray in each nostril once daily for maintenance therapy.
Maximum total daily doses should not exceed 2 sprays in each nostril (total dose, 200 mcg/day). There is no evidence that exceeding the recommended dose is more effective.
Adolescents And Children (Aged 4 Years and Older)
The recommended starting dosage in adolescents and children, aged 4 years and older is 1 spray in each nostril once daily (total daily dose, 100 mcg). Patients not adequately responding to 1 spray in each nostril may use 2 sprays in each nostril once daily (total daily dose, 200 mcg).
Once adequate control is achieved, the dosage should be decreased to 1 spray in each nostril once daily.
The maximum total daily dosage should not exceed 2 sprays in each nostril (200 mcg/day). There is no evidence that exceeding the recommended dose is more effective.
SIDE EFFECTS
Systemic and local corticosteroid use may result in the following:
Epistaxis, nasal ulceration, Candida albicans infection, nasal septal perforation, and impaired wound healing [see WARNINGS AND PRECAUTIONS]
Cataracts and glaucoma [see WARNINGS AND PRECAUTIONS]
Immunosuppression [see WARNINGS AND PRECAUTIONS]
Hypercorticism and adrenal suppression [see WARNINGS AND PRECAUTIONS]
Effect on growth [see WARNINGS AND PRECAUTIONS]
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So while this product seems to be okay for daily ongoing use, there could be side effects.
I suppose sticking water and salt up your nose everyday could have side effects too.
Good Luck!