Protocol has been updated
For preventative or Prophylaxis
Vitamin D3 1000-3000 iu/day. Note RDA (Recommended Daily Allowance) is 800-1000 iu/day.
The safe upper-dose daily limit is likely < 4000 iu/day. [1-16]
• Vitamin C 500 mg BID (twice daily) and Quercetin 250 mg daily. [17-28] Note that prolonged
high dose quercetin has very rarely been associated with hypothyroidism. [29,30] Quercetin
should be used with caution in patients with hypothyroidism and TSH levels should be
monitored.
• Melatonin (slow release): Begin with 0.3mg and increase as tolerated to 2 mg at night. [31-38]
• Zinc 30-50 mg/day (elemental zinc). [17,24,26,27,39-43]
• B complex vitamins [44-48]
• Optional: Famotidine 20-40 mg/day [49-55]. Low level evidence suggests that famotidine MAY
reduce disease severity and mortality. However the findings of some studies are contradictory.
While it was postulated that famotidine inhibits the SARS-CoV-2 papain-like protease (PLpro) as
well as the main protease (3CLpro) this mechanism has been disputed.[52] Furthermore, a single
study suggested that users of PPI’s had a significantly increased odds for reporting a positive
COVID-19 test when compared with those not taking PPIs, while individuals taking histamine-2
receptor antagonists were not at elevated risk.[56] This data suggest that famotidine may be the
drug of choice when acid suppressive therapy is required.
• Ivermectin for pre- and postexposure prophylaxis (see ClinTrials.gov NCT04422561 &
NCT04425850). 200ug/kg immediately then repeat in 72 hours.
•
Ivermectin for prophylaxis in high risk individuals. 150-200ug/kg (or 12 mg) ivermectin
weekly.
• Optional/Experimental: Interferon-α nasal spray for health care workers [54]
Updated protocol omits quercetin but he includes it in his video(47:12), hard to know if it is a mistake or not.
See link for additional information if symptomatic