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Old 01-23-2010, 06:58 AM
 
214 posts, read 1,791,637 times
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My husband has had three Urinary track infections in a row. He has taken two kinds of antibiotics and none of them have worked. Everytime he comes off the antibiotic the infection returns in a couple days. He had a CT scan done of his abdomen after the second one and everything was fine. The Uroligist said the antibiotics he was taking (Ciprofloxacin 750's for 20days) would clear it up. That was during the second infection. He is down to his last pill today and has already told me that he can tell it did not work and expects it to be back in full in a couple days. This will be the fourth infection now in a row. Any ideas what may be going on? He has not had any blood work done through all of this. Would some blood work maybe help indicate something? We are desperate for some answers.
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Old 01-23-2010, 07:16 AM
 
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I would suggest seeing an infectious diseases specialist. Firstly, if there is ANY hint of prostatic infection, that would need SIX WEEKS of antibiotics, as the prostate is a privileged space. Second, whoever is treating him needs to get a urine (CLEAN CATCH) at least a WEEK after stopping antibiotics, and send it for culture and susceptibility testing.

Urologists are GREAT at what they are good at (surgery) but they're NOT wonderful treating infections.
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Old 01-23-2010, 07:21 AM
 
Location: In the real world!
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Does he drink soda's? If so have him stop. I have a niece that can drink a soda and by the next day she has a kidney infection.. Odd but true. Also I hope he knows not to drink grapefruit juice while on these meds... (You'd be surprise how many people don't know that.)

Yes, I would insist on blood work, they need to look at everything to see if they can find out the cause of these ongoing infections. Good Luck in finding the cause.
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Old 01-23-2010, 07:24 AM
 
214 posts, read 1,791,637 times
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Quote:
Originally Posted by Viralmd View Post
I would suggest seeing an infectious diseases specialist. Firstly, if there is ANY hint of prostatic infection, that would need SIX WEEKS of antibiotics, as the prostate is a privileged space. Second, whoever is treating him needs to get a urine (CLEAN CATCH) at least a WEEK after stopping antibiotics, and send it for culture and susceptibility testing.

Urologists are GREAT at what they are good at (surgery) but they're NOT wonderful treating infections.

His prostate was checked and it appeared to be fine. He had a urine culture a few days after coming off of the third antibiotic and it showed bacteria elements.
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Old 01-23-2010, 07:25 AM
 
214 posts, read 1,791,637 times
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Originally Posted by Laura707 View Post
Does he drink soda's? If so have him stop. I have a niece that can drink a soda and by the next day she has a kidney infection.. Odd but true. Also I hope he knows not to drink grapefruit juice while on these meds... (You'd be surprise how many people don't know that.)

Yes, I would insist on blood work, they need to look at everything to see if they can find out the cause of these ongoing infections. Good Luck in finding the cause.
He is not a soda drinker so that is definitely not it. We did have some grapefruit juice during one of his infections and he did drink it so I guess that wouldn't help the situation. Thanks for the tips.
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Old 01-23-2010, 07:57 AM
 
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Grapefruit juice is only a problem (and it has to be drunk in ENORMOUS quantities) if a drug is metabolized through the cytochrome P450 3A4 system. Ciprofloxacin is metabolized through P450 1A2, not 3A4.

Again, was a prostatic massage done and urine cultured FOLLOWING the prostatic massage?

As I said above, urologists are SURGEONS. That's what they do best. But ID specialists see this stuff EVERY DAY.
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Old 01-23-2010, 09:41 AM
 
214 posts, read 1,791,637 times
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He thinks a urine culture was done when this first started and he gave a urine sample with our family MD. We never recieved the results of that test but we knew he had an infection and blood in his urine from the test they ran at the doctors office. That was before any antibiotics. When the infection did not clear he was referred to the Urologist and that is when he had his prostate checked. Prostate was fine. When it came back the third time he could not get an appointment with the Urologist so he went back to the family MD and gave another urine sample. It showed blood in the urine and they called with the results from this culture and said it had bacteria elements. I don't think he will make it 7 days after going off antibiotics. It seems like after three days he is very uncomforatable. Maybe he could get the results of the first culture and that could point them in the right direction.

Thanks for your advise it is greatly appreciated. He has an appointment with the Urologist on Monday and he will ask about seeing the specialist.
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Old 01-23-2010, 10:02 AM
 
7,079 posts, read 35,123,338 times
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The point I was trying to make is that he should be OFF antibiotics for about a week before another culture is done. There is something called a 'post-antibiotic' effect that prevents bugs from growing. AND what might have grown in the first culture, may not have grown in subsequent cultures because of the antibiotics changing the flora in the bladder.

And you should ask about sending a culture for 'fastidious' organisms.
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Old 01-23-2010, 06:26 PM
 
Location: Dallas TX
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I would go get a second opinion. Obviously there is a big problem and the doctor isn't getting to the bottom of it.
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Old 01-23-2010, 06:48 PM
 
Location: N. CA
127 posts, read 277,614 times
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I am just wondering if you have been checked for a vaginal infection. If you are having intercourse, it could be possible that you keep passing it back to him. Maybe you should both take antibiotics just to be sure.
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