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Old 09-18-2014, 09:19 PM
3 posts, read 2,769 times
Reputation: 10


A psychiatrist prescribed me Lamictal XR (lamotrigine) 100 mg. tablets the other day, but I haven't filled the 'script yet. A healthcare worker once told me a potential side effect of the drug is that your flesh could literally melt off of your body. I'm leaving out some details, but what he told me was absolutely disgusting. Now, I've heard that the drug is quite effective at managing depressive symptoms. However, I'm not so sure the side effect profile is something I can [mentally] handle.

Are we a fan of trying Lamictal XR?

Peace and freedom
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Old 09-19-2014, 11:30 PM
3 posts, read 11,194 times
Reputation: 13
The rare side effect you are talking about is called Stevens-Johnson Syndrome (google it - it is a horrible rash - if anything that looks like it develops stop taking the med and go to an emergency room for treatment.) It happens in maybe 1-2% of the patients taking the medicine. It happens early on in treatment, maybe in the first couple of weeks of treatment. If you decide to take LamictilXR you MUST take it every single day. If you skip a single day you must restart the medicine at the lowest dose it was prescribed. e.g. you just can't pick up and resume taking it at a dose higher than the starting dose. I hope your psychiatrist went over all of this with you. Your so-called healthcare worker should be thrashed for saying what s/he said to you.
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Old 09-21-2014, 04:09 AM
Location: Cushing OK
14,545 posts, read 18,413,482 times
Reputation: 16831
I took it for several years. I didn't get a devistating skin disease, but though I was taking two others I have become very intollerant of sun. I get a dry skin type rash on my cheek when in the sun now, with no meds for a couple of years. It will give you a marked sensitivity to sun and do take all the warnings serious. It may have been from a combo of that and welbrutain or not, but I have a scaley, dry area on my lower cheek which only seemes to feel better with cortozine cream, but has never cleared. Sun causes it to return. Staying out of the sun seems the only thing to keep it away.

My pdoc never said anything about the rash but my medical doctor said this wasn't, however since the pdoc didn't say anything I made sure to look up anything and everything since. It also with the ad pushed me WAY too manic.
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Old 09-21-2014, 05:15 AM
1,328 posts, read 2,002,499 times
Reputation: 6334
I have a family member on it. She's had great success with it. The skin thing is happens to such a small population and the upside of taking it is great. I say try it. Good luck to you.
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