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Old 06-11-2015, 09:16 PM
 
Location: Asheville, NC
12,626 posts, read 31,909,908 times
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What kind of results have you had with it?
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Old 06-14-2015, 11:33 AM
 
1,950 posts, read 3,511,331 times
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GABA supplements don't cross the blood brain barrier and thus have no impact on anxiety.

Last edited by west seattle gal; 06-14-2015 at 11:58 AM..
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Old 06-14-2015, 08:34 PM
 
Location: NYC
16,061 posts, read 26,641,910 times
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It's done nothing for me.
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Old 06-15-2015, 01:54 PM
 
Location: Asheville, NC
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Hmm, sounds like other natural remedies.
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Old 06-17-2015, 02:45 PM
 
Location: God's Country
5,182 posts, read 5,203,852 times
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Quote:
Originally Posted by west seattle gal View Post
GABA supplements don't cross the blood brain barrier and thus have no impact on anxiety.
Another perspective:

Natural StressCare: GABA - Natural Valium, or Is It?

(snip)

In conventional medical circles it's thought that GABA will not pass through the blood-brain barrier, and so taking it orally shouldn't have much effect on mood. Nevertheless, many people report that taking GABA has an anti-anxiety action, and at least one study provides evidence that it does.[SIZE=2]2[/SIZE]

It turns out that while GABA doesn't pass through the blood brain barrier ... it can make its way into the peripheral aspects of the CNS (such as the dense connections in the gut.) Also ... the hypothalamus, the emotional neuroendocrine control center of the brain ... is outside of and thus not protected by the blood brain barrier. These two factors could explain the research / practice gap here.

Alternatively, one can take the amino acid theanine instead. Theanine is converted to several useful calming and mood-elevating substances in the brain, including GABA.[SIZE=2]3,4[/SIZE] So one can use theanine as a kind of "bank shot" to get around the blood brain barrier issue with respect to GABA.

(snip)
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Old 06-17-2015, 05:41 PM
 
Location: A coal patch in Pennsyltucky
10,263 posts, read 10,505,282 times
Reputation: 12559
Quote:
Originally Posted by Calvert Hall '62 View Post
Another perspective:

Natural StressCare: GABA - Natural Valium, or Is It?

(snip)

In conventional medical circles it's thought that GABA will not pass through the blood-brain barrier, and so taking it orally shouldn't have much effect on mood. Nevertheless, many people report that taking GABA has an anti-anxiety action, and at least one study provides evidence that it does.[SIZE=2]2[/SIZE]

It turns out that while GABA doesn't pass through the blood brain barrier ... it can make its way into the peripheral aspects of the CNS (such as the dense connections in the gut.) Also ... the hypothalamus, the emotional neuroendocrine control center of the brain ... is outside of and thus not protected by the blood brain barrier. These two factors could explain the research / practice gap here.

Alternatively, one can take the amino acid theanine instead. Theanine is converted to several useful calming and mood-elevating substances in the brain, including GABA.[SIZE=2]3,4[/SIZE] So one can use theanine as a kind of "bank shot" to get around the blood brain barrier issue with respect to GABA.

(snip)
I've tried GABA and currently have a bottle of theanine (Doctor's Best Suntheanine) and neither have done anything for me
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Old 06-17-2015, 05:45 PM
 
Location: San Antonio, TX
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I'm taking 5-HTP, which has really helped with my anxiety. The first couple of times that you take it, it can cause diarrhea, but that goes away pretty quickly.
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Old 03-16-2018, 08:58 PM
 
Location: Southern California
29,267 posts, read 16,568,121 times
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Since there is so much discussion about anxiety thought I'd bring up Gaba again. Some can take it and some cannot. I take it just fine and it's part of my sleep combo 500mg every night. Here is a posting from Alt Med group.

//www.city-data.com/forum/alter...ess-helps.html

Maybe even a lower dose than 500mg to start.

Right now a friend is waking up with horrid monster anxiety in the mornings. Trying to talk her into working with Gaba.
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Old 03-31-2018, 02:26 PM
 
Location: East Texas
506 posts, read 646,709 times
Reputation: 729
GABA made me feel so weird and awful I threw it out.
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Old 03-31-2018, 07:33 PM
 
Location: Unlike most on CD, I'm not afraid to give my location: Milwaukee, WI.
1,768 posts, read 4,121,684 times
Reputation: 4044
Forget GABA, l-theanine, or any of the supplements touted to help with anxiety or depression. The only way these things will "help" you is if you are very prone to getting the placebo effect.
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