New drug may be cure for dementia and other brain ailments (impeachment, drugs)
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Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome , prevent noise-related hearing loss, fight certain types of prostate cancer , and even enhance cognition in healthy animals.
Having been in research for the last 20 years, including the last 3 and a half in neuroscience, this is great news, but remember many drugs show amazing results and promise in animal models, dozens or more every year, but getting those drugs to do the same thing in humans that they do in rodents or even non-human primates is the tricky part.
Many compounds/drugs work great, almost miracle-like in vitro (in cells), but getting those same results in vivo (in animals) is really hard, and lets say you do get good or great results in animal models, getting that to work in humans with similar results, no so easy, I wish it was!
I saw it as well, but honestly....it is still a long ways from being used on humans and showing human results. Its certainly got potential....but until its got some evidences im not getting too excited about it.
They can cure anything in mice. People ain't mice. I remember when clioquinol worked great to clear Alzheimer's plaques in mice but it didn't work in people so well. I think it actually may help a bit. I used it on my father. But it's an old drug and no $ to make marketing it. There is a nerve growth factor called Cerebrolysin that helps.
Note - someone please move this to health and wellness so we don't have so many political references. Biden - Trump! BIDEN-TRUMP!! Does it have to dominate every thread?
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