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Old 06-08-2021, 07:09 PM
 
Location: Wisconsin
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Quote:
Originally Posted by DrPibbs View Post
Oh ok so in virology supercharge means to splice in something to make it more lethal.
Correct.


And as the article says, the double CGG sequence has never been seen to occur in nature, but it's the go to sequence with gain of function labs.

I mean, how many more nearly statistically impossible coincidences do we need to see?

1) The first infections are in and around one of the three labs in the world which experiment with coronavirus.

2) Then COVID-19 has a common double CGG sequence used in the Wuhan lab, but never seen in nature.

3) Then we learn that Chinese medical researchers created mice with ‘humanized lungs’ mere months before the pandemic began.

What are the odds of this happening by happenstance, a billion to one?
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Old 06-08-2021, 07:09 PM
 
Location: King County, WA
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This Nature article gives a more balanced view and addressed many of the issues:

The COVID lab-leak hypothesis: what scientists do and don’t know
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Old 06-08-2021, 07:18 PM
 
Location: Wisconsin
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Quote:
Originally Posted by Spartacus713 View Post
Yep. It is manmade. And Dr. Fauci was in on it with the CCP.
And a note to Fauci, we don't think the Chinese purposely released the virus inside China. We think careless scientists accidentally released it onto the people of Wuhan. Now, it's debatable whether the CCP knowingly allowed people infected with the virus to travel around the world, w/o telling anyone.

Fauci defends China, claims it’s ‘far out’ COVID was created in a lab

“The idea, I think, is quite far-fetched that the Chinese deliberately engineered something so that they could kill themselves."

I don't think people are dumb enough to think the CCP infected millions of it's own people, as a clumsy and idiotic way to spread the virus. If Xi wanted to unleash a plague on the world, he would have made sure it's origin was in Europe or the US, preferably near one of their infectious disease labs, not at China's own freaking coronavirus lab.
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Old 06-08-2021, 07:24 PM
 
Location: Wisconsin
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Quote:
Originally Posted by rjshae View Post
This Nature article gives a more balanced view and addressed many of the issues:

The COVID lab-leak hypothesis: what scientists do and don’t know
Thanks, it's always good to read other info.

Interesting snippet:

Nobel laureate and professor emeritus at the California Institute of Technology in Pasadena, as saying that viruses don’t usually have that particular code for arginine, but humans often do — a “smoking gun”, hinting that researchers might have tampered with SARS-CoV-2’s genome.

The other link had scientists who made a point of saying that the double CCG has never been seen in nature. The professor in your link simply says "viruses don’t usually have that particular code for arginine." So is that code never been seen in nature, or is it just not usually seen?


There is link inside your link, where it says:


There are several curious features about this insert but the oddest is that of the two side-by-side CGG codons. Only 5% of SARS2’s arginine codons are CGG, and the double codon CGG-CGG has not been found in any other beta-coronavirus. So how did SARS2 acquire a pair of arginine codons that are favored by human cells but not by coronaviruses?


This seems to say that the double CGG favored by gain of function labs does not exist in nature.
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Old 06-08-2021, 07:25 PM
 
19,573 posts, read 8,519,803 times
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Quote:
Originally Posted by Wapasha View Post
And a note to Fauci, we don't think the Chinese purposely released the virus inside China. We think careless scientists accidentally released it onto the people of Wuhan. Now, it's debatable whether the CCP knowingly allowed people infected with the virus to travel around the world, w/o telling anyone.

Fauci defends China, claims it’s ‘far out’ COVID was created in a lab

“The idea, I think, is quite far-fetched that the Chinese deliberately engineered something so that they could kill themselves."

I don't think people are dumb enough to think the CCP infected millions of it's own people, as a clumsy and idiotic way to spread the virus. If Xi wanted to unleash a plague on the world, he would have made sure it's origin was in Europe or the US, preferably near one of their infectious disease labs, not at China's own freaking coronavirus lab.

That does currently appear to be the most plausible explanation.
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Old 06-08-2021, 07:33 PM
 
Location: The Republic of Texas
78,863 posts, read 46,624,265 times
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Quote:
Originally Posted by Wapasha View Post
Some experts have noticed that a gene sequence never seen in nature, but common in gain of function labs, is seen inside COVID-19.

Also, Chinese medical researchers created mice with ‘humanized lungs’ mere months before the pandemic began, suggesting a gain-of-function focus. Hmmm, another coincidence?


The Wall Street Journal is also reporting on this:

Experts Assert ‘Rare’ Genome Sequencing Shows Coronavirus Bioengineered, Optimized for Human Infectivity

Lawrence Livermore has considerable expertise on biological issues. Its assessment drew on genomic analysis of the SARS-COV-2 virus, which causes Covid-19, they said.

Scientists analyze the genetic makeup of viruses to try to determine how they evolved and spread in the population. Proponents on both sides of the debate over the origins of Covid-19 have cited such analysis to try to make their case.


In the case of the gain-of-function supercharge, other sequences could have been spliced into this same site. Instead of a CGG-CGG (known as “double CGG”) that tells the protein factory to make two arginine amino acids in a row, you’ll obtain equal lethality by splicing any one of 35 of the other two-word combinations for double arginine. If the insertion takes place naturally, say through recombination, then one of those 35 other sequences is far more likely to appear; CGG is rarely used in the class of coronaviruses that can recombine with CoV-2.

In fact, in the entire class of coronaviruses that includes CoV-2, the CGG-CGG combination has never been found naturally. That means the common method of viruses picking up new skills, called recombination, cannot operate here. A virus simply cannot pick up a sequence from another virus if that sequence isn’t present in any other virus.



Quay and Muller point to the “double CGG” sequence as the “damning fact” suggesting a laboratory origin:
Proponents of zoonotic origin must explain why the novel coronavirus, when it mutated or recombined, happened to pick its least favorite combination, the double CGG,” they wrote. “Why did it replicate the choice the lab’s gain-of-function researchers would have made?

“At the minimum, this fact — that the coronavirus, with all its random possibilities, took the rare and unnatural combination used by human researchers — implies that the leading theory for the origin of the coronavirus must be laboratory escape.”
The "gain of function" CGG-CGG signature is all over it.
It was unleashed as bio-warfare, to have an excuse to cheat an election.
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Old 06-08-2021, 07:37 PM
 
Location: Orange County, CA
2,367 posts, read 909,441 times
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Virology is not my field. At first I thought "supercharge" had something to do with the virus surfaces being positive or negatively charged. It's frustrating for those of us who can't understand the science.
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Old 06-08-2021, 07:59 PM
 
29,939 posts, read 39,464,356 times
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If you haven't seen this it is worth a watch. It's 2.5 hrs long but worth it.

https://youtu.be/Tn_b4NRTB6k
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Old 06-08-2021, 08:02 PM
 
Location: Southeast US
8,609 posts, read 2,308,762 times
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Quote:
Originally Posted by Wapasha View Post
Correct.

the double CGG sequence has never been seen to occur in nature, but it's the go to sequence with gain of function labs.
sorry for editing your post, but for those in the back of the short bus.
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Old 06-08-2021, 08:02 PM
 
9,434 posts, read 4,253,620 times
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Quote:
Originally Posted by rjshae View Post
This Nature article gives a more balanced view and addressed many of the issues:

The COVID lab-leak hypothesis: what scientists do and don’t know
Great article. Thanks for the link. I love nature.
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