Ivermectin: How false science created a Covid 'miracle' drug (Miami, dollars, bias)

[hooligan]

Originally Posted by beachGecko

Omicron causes severe disease so infrequently, they would need a trial having at least 20,000 people to be statistically powered enough to show effect. And that's the minimum.

As a result any study now will show no statistical effect.

How do you arrive at that 20K number?

The UMN trial was started in Jan of 2021, BTW. Nearly a year before the first confirmed case of Omicron in the US. https://clinicaltrials.gov/ct2/show/NCT04510194

[clutchcargo777]

Why do the Ivermectn clinical studies take 10x longer then the vaccine trials?

[Bitey]

Originally Posted by hooligan

Of course I have.

You're either full of it, Option A (no you haven't), or you're full of it Option B (you're deliberately misrepresenting the results), or you simply didn't comprehend what you were reading.

[beachGecko]

Originally Posted by hooligan

How do you arrive at that 20K number?

The UMN trial was started in Jan of 2021, BTW. Nearly a year before the first confirmed case of Omicron in the US. https://clinicaltrials.gov/ct2/show/NCT04510194

You can use this online calculator, I put in rough numbers and got 15688.

https://clincalc.com/stats/samplesize.aspx

My power is 80%, alpha is 0.05, incidence in Ivermectin arm is 0% and in placebo 0.1% (severe disease).

Of course, alpha = 0.05 is on the higher side, if I adjust alpha to 0.01, I get 23344.

When I told you 20,000, I ball parked that figure from my understanding of effect and sample sizes. Quite a good ballpark.

[vegasrollingstone]

Originally Posted by beachGecko

We have very intelligent posters on this forum

Science is based on cause and effect, get a clue.

[beachGecko]

Originally Posted by vegasrollingstone

Science is based on cause and effect, get a clue.

Stick to talking about topics you're educated in, like eating PJ sandwiches.

[hooligan]

Originally Posted by Bitey

You're either full of it, Option A (no you haven't), or you're full of it Option B (you're deliberately misrepresenting the results), or you simply didn't comprehend what you were reading.

Whatever you say.

https://jamanetwork.com/journals/jam...stract/2789362

https://www.nature.com/articles/d41586-021-02081-w

https://www.wfyi.org/news/articles/i...tion-americans

https://academic.oup.com/ofid/articl...fab645/6509922

[hooligan]

Originally Posted by beachGecko

You can use this online calculator, I put in rough numbers and got 15688.

https://clincalc.com/stats/samplesize.aspx

My power is 80%, alpha is 0.05, incidence in Ivermectin arm is 0% and in placebo 0.1% (severe disease).

Of course, alpha = 0.05 is on the higher side, if I adjust alpha to 0.01, I get 23344.

When I told you 20,000, I ball parked that figure from my understanding of effect and sample sizes. Quite a good ballpark.

Thanks.

Unfortunately, the UMN "COVID-OUT" trial is only targeted at 1350 participants, I believe.

So we'll ignore the results even if it says Ivermectin is super effective, right?

[DannyHobkins]

Had covid in January 2022, my doctor prescribed Ivermectin to me, however it was sold out at CVS and Walgreens, so didnt take it.

[clutchcargo777]

Originally Posted by DannyHobkins

Had covid in January 2022, my doctor prescribed Ivermectin to me, however it was sold out at CVS and Walgreens, so didnt take it.

Was it "sold out" or was it "unavailable". There is a difference.