I lived there once...but that was 1974-77.
I haven't been on US Route 1 in Wells in a LONG time. My brother was recently on it, however, along with Mile Road, the connector between that and Wells Beach. He said that little seems to have changed there since the last time I was by that.
Wells is Exit 19 from I-95/Maine Turnpike. The first exit involving Portland is 44 (I-295 North). Go one exit further for the Maine Mall and ME Route 114 (Exit 45) and you're looking at 26 miles each way. And that's only South Portland.
Good luck with your Wells quest!
P.S. If coming off of I-95/Maine Turnpike, take a left to get into the town center and to US Route 1. Take a right for ME Route 109 to Sanford. There's very little to see in between. I know because I lived in the sticks west of that way back when!