Do you have any general ideas of where you'd like to live in Sanford, or what type of housing or community? That can also help identify an agent that would be a good fit for your needs.
One suggestion would be to identify if there are certain neighborhoods or types of communities(i.e. gated, golf, historic, rural/farm, etc) then perhaps ask around for a Realtor that may have specific experience buying/selling in those neighborhoods.
If you are interested in Historic properties, you might consider posting this question to Sanford's Historic Neighborhood Yahoo Group:
historic-sanford-nc : Historic Sanford North Carolina
As you may already know, Sanford has four National Register Historic Districts, three of which are residential: Hawkins Avenue, Lee Avenue, and Rosemount McIver Park
Houses in these districts are eligible for historic preservation tax *credits*(not just deductions, actual credits) of 30% from your NC state income tax on projects over $25k. If one is interested in older homes, this is a deal that really can't be had for any other type of home, and is a huge advantage.
Here is some more info on Sanford's historic districts:
Historic Preservation, Planning & Development (http://www.sanfordnc.net/Planning/historic_preservation.htm - broken link)
Here is some more info on historic tax credits:
Historic Preservation Tax Credits in North Carolina
I hope all of that is helpful, and good luck on your search! Sanford may not be a huge metropolis, but we do have a similar variety of home/community types that the larger cities have, so I suspect you can find something to fit your needs.
Al
P.S.
BTW, if you aren't aware, don't miss the chance to see the "Lee County Second Century" project presentation and community party this Thursday, October 2nd at Depot Park from 7pm to 9pm. This is a new marketing effort for Lee County and Sanford, that will include a new logo, motto, and marketing plans to promote Sanford and Lee County externally. It is very exciting.
More info on the project and community party can be found here:
Sunday Column: Why the 2nd Century Project Matters to Business « Chamber Chat