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If you like art museums and concerts, you get a two-fer with the NC Museum of Art. I'd look near there for a place to live. I'm sure a house there will cost more than one in Mebane, but time has a value.
If he will be working in RTP you might like northern Durham County or around Hillsborough. It's not the closest to RTP, but would be a lot better than Mebane. It takes me 30 min every day to get from Chapel Hill to Saxapahaw. I can't see you going from Mebane to RTP in 30. I would allow 30 from my house to Mebane, too. My kids have friends up that way.
Be aware that you are going to pay a premium for housing that is a short commute to RTP.