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Old 05-09-2021, 12:15 PM
 
2,119 posts, read 4,166,775 times
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I have been part of a Wake Forest study for Covid19 where daily they ask if I consider myself in good health, any symptoms, any new tests or vaccinations etc etc.? I started about 6 months ago and way before my vaccination. A few days before my vaccination I was asked to do part 2 a Scanwell test which is blood tested monthly to look for how long antibodies if you have any stay. Igg and Igm are tested. The first pre-vaccination showed a slight positive to Igm indicating recent (acute)exposure to the virus. Two day later received the J & J. 4 weeks later today am tested and still no evidence of Igg which would indicate antibodies being made. So now wondering if my vaccination changed anything. Have to wait another 4 weeks to see but I was told Igg is created with the vaccination and is indicative of protection .. Anyone else doing this?
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Old 05-09-2021, 12:42 PM
 
Location: Raleigh, NC
19,429 posts, read 27,808,716 times
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I am doing a similar covid study through NIH. Five visits over 15 months for a blood draw, weekly emailed questionnaire. They told me that the type of antibodies that they were looking for were different than the ones I would develop from the vaccine.

I also give blood every 60-70 days. The Red Cross has been doing free antibody tests for all donors for quite a few months. I've always been negative until my donation following my Moderna vaccine. Now I'm "reactive" for antibodies which is what occurs after vaccines. (Reactive is NOT the same as a "positive" result. Positive would mean you actually had covid at some point.)
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Old 05-09-2021, 01:39 PM
 
Location: North Carolina
715 posts, read 1,038,510 times
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Quote:
Originally Posted by Jkgourmet View Post
I am doing a similar covid study through NIH. Five visits over 15 months for a blood draw, weekly emailed questionnaire. They told me that the type of antibodies that they were looking for were different than the ones I would develop from the vaccine.

I also give blood every 60-70 days. The Red Cross has been doing free antibody tests for all donors for quite a few months. I've always been negative until my donation following my Moderna vaccine. Now I'm "reactive" for antibodies which is what occurs after vaccines. (Reactive is NOT the same as a "positive" result. Positive would mean you actually had covid at some point.)

Same here. Donated blood before my vaccination with the pfizer and my Red Cross antibody test was negative. I donated weeks after my second dose of the vaccine and the test came back "reactive".
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Old 05-10-2021, 07:58 AM
 
1,501 posts, read 1,726,213 times
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I don't know the particulars of the tests you are having done, but my understanding is that multiple antibodies are produced after exposure to the virus corresponding to different parts of the virus some of which are more effective than others. When you get the vaccine, the antibodies produced are limited by what proteins are present in the vaccine (just one in Moderna and Pfizer, presumably more in J&J). It is possible they are testing for antibodies that are produced in response to the virus but not the vaccine.

With hepatitis, they can differentiate between people who have been exposed vs vaccinated by looking for these different antibodies. Might be something similar going on here.
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Old 05-10-2021, 08:05 AM
 
Location: Raleigh, NC
4,542 posts, read 3,741,311 times
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Quote:
Originally Posted by bcattwood View Post
I don't know the particulars of the tests you are having done, but my understanding is that multiple antibodies are produced after exposure to the virus corresponding to different parts of the virus some of which are more effective than others. When you get the vaccine, the antibodies produced are limited by what proteins are present in the vaccine (just one in Moderna and Pfizer, presumably more in J&J). It is possible they are testing for antibodies that are produced in response to the virus but not the vaccine.

With hepatitis, they can differentiate between people who have been exposed vs vaccinated by looking for these different antibodies. Might be something similar going on here.

Correct. The OP probably had a test that was targeting a different parts of a protein, and doesn't really gauge your immune reaction to the vaccine. Here's a test that's only $23 and does test for antibodies that are produced after the 3 vaccines we have here and is FDA approved. However, you need a MD/PA or NP's NPI number so you can maybe find someone who can order it for you:

https://www.code1supply.com/rapid_test_kit_each
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