I agree with Chris...
Well... is your company paying for the room?
If so, go with the Sheraton at West & Russell.... If you wanna be downtown, I would choose the Holiday Inn City Centre on 8th Street. It's within walking distance of the downtown bars... Both are probably similarly priced... Another good hotel is the Club House Hotel & Suites on Louise Avenue.... It's near a shopping district...it's attached to a Carino's restaurant (Italian). Most of the nightlife is downtown. The exceptions would be Nutty's & Buck's. Both attract the younger crowd. Nutty's has a location on West Avenue, near the Arena/Convention Center. Buffalo Wild Wing's is right next to it...another popular bar.
As for steakhouses, the Tea Steakhouse is awesome... just a few miles outside the city limits of SF...
Foley's & Minerva's in SF are good steak places.