Paterson is located northeast of Newark on Highway 80; Newark Liberty International Airport (NLIA), located just a few more miles to the south, is one of the busiest airfields in the country. International flight service is offered by at least 20 of NLIA's resident airlines, while domestic service is handled by about 15 more providers and several air charters. Ground travelers can jump on Amtrak at Penn Station in Newark or the Greyhound/Trailways Bus Service which also serves the city.
Interstate 80 runs east and west through Paterson, which is approached from the south by State Highway 19. Market and Main Streets intersect in the city center, providing a reasonable directional reference in a municipality where the street grid bends slightly to follow the river that runs through it. Other major routes are McLean Boulevard, River Drive, and Randolph Avenue, which are laid out from north to south, and the east-west Broadway. The city is served by the Main Line of the New Jersey Transit railway and bus systems, in addition to the specialized transport programs offered through Passaic County Para Transit.