Both two of the most interesting/vibrant urban neighborhoods in the US for sure. Love the feel in each.
I will say, though, that Philadelphia's Manayunk is a bit more treacherous for a non-pedestrian due to the very steep grade and incredibly narrow streets. Not a fun place for a car owner by any measure:
https://maps.app.goo.gl/QQ6iUBsr4r9ETcXA6