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When one bottle is near empty, open and use the new one. When that one can hold the rest from the near empty one just turn the bottle upside down and put it on top of the new bottle. We use it for hot sauce, ketchup, hand lotion, pancake syrup, etc.
We have one of those roller things that fits on the tube of tooth paste. You roll it as you go and the waste is less than 1% of the tube.