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I agree about University City since 30th street to 38th street has a lot of restaurants and clothing stores while the bridge separates center city and university city at 23rd to 29th street.
The University Hill area in Syracuse may qualify, as it is separated by I-81 and the hill serves as a separating land feature. It is home to 3 hospitals, a few hotels, a couple of business districts and 3 institutions of higher learning off the top of my head. Welcome to University Hill!
I don't consider Uptown Dallas as a "second CBD" or even the Galleria, based off of the OP's definition. Uptown/Victory Park is more of an extension of Downtown Dallas, especially the areas near Klyde Warren Park. The Galleria/LBJ corridor is more of an office park area. Not very pedestrian friendly, although this may change with the Midtown project. Preston Center may qualify as a secondary CBD, but I can see arguments against it as well.
If in Atlanta, Midtown is too attached to Downtown (yes they are next to one another only separated by Lindon Avenue and the sudden appearance of numbered east/ west streets, starting with 3rd Street with North Avenue being "1st Street" and Ponce de Leon Avenue being "2nd Street") than how about our uptown Buckhead district. Especially along Peachtree between Piedmont and Lenox Square, it looks and acts like a second downtown with highrise office buildings and tons of shopping (really MUCH more shopping than Downtown these days with Lenox Square and Phipps Plaza cater cornered across Peachtree from one another with their six department stores and hundreds of boutiques) Others call it an "edge city", but being within the City of Atlanta I am uncertain if it would meet the criteria for an "edge city" in the true sense like Perimeter Center and Cumberland/ Galleria in the North Atlanta suburbs, but NOT inside the Atlanta City limits.
In Phoenix.... Tempe has begun to develop a downtown-like area but I don't feel comfortable actually labeling it a downtown area, it's a few years removed from that.
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