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Old 05-09-2018, 06:33 AM
 
723 posts, read 1,005,332 times
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Humira works pretty well. Have been on it several times but then lost it due to change in medical insurance. Just got on it again and do not ever want to NOT be on it again or another one as good. I do realize that auto-immune diseases are THE fastest growing area of illnesses in the U.S. WHY??? Seems like about half of all ads now on TV are for Humira or a competitor and they all cure like 3-4 different things not just Psoriasis.
Like Crohn's Disease, Rheumatoid Arthritus, others??? Amazing.

 
Old 05-09-2018, 11:47 AM
 
8,226 posts, read 3,423,206 times
Reputation: 6094
Quote:
Originally Posted by SailCT View Post
Humira works pretty well. Have been on it several times but then lost it due to change in medical insurance. Just got on it again and do not ever want to NOT be on it again or another one as good. I do realize that auto-immune diseases are THE fastest growing area of illnesses in the U.S. WHY??? Seems like about half of all ads now on TV are for Humira or a competitor and they all cure like 3-4 different things not just Psoriasis.
Like Crohn's Disease, Rheumatoid Arthritus, others??? Amazing.
Drugs like Humira suppress the immune system, and that is how they reduce the symptoms of autoimmune disorders. Suppressing the immune system for long periods of time is not a good idea, because the immune system helps prevent infections, cancer, etc.

If autoimmune disorders are growing fast, it's probably related to the unnatural modern lifestyle.

I was writing about metabolic syndrome (MetS) in the psychology forum, because it is related to psychological disorders, and to psychiatric drugs, as well as to heart disease, cancer, diabetes, dementia, etc. MetS is probably also a factor in autoimmune disorders.

Recent research has been showing what some medical scientists have been saying for decades -- MetS can be caused by high consumption of refined sugar, along with physical inactivity. In other words, the typical American lifestyle.

We did not evolve to ingest sugar apart from natural food, such as fruit. When sugar is eaten separately, with no fiber, too much energy is rapidly made available to the cells. Insulin does its job of shoving glucose into the cells, but it's too much, and eventually the cells become insulin resistant, in self-defense.

Insulin resistance of the cells in turn causes insulin production to increase.

High insulin levels in the blood are damaging, possibly contributing to artery disease.

And the mitochondria within each cell become overwhelmed by too much glucose. The lack of physical activity means most of the glucose is not being used for muscle contractions.

All this eventually leads to chronic inflammation. Chronic inflammation is the foundation of many of the current chronic and/or fatal diseases, such as type 2 diabetes, artery disease, Alzheimer's disease, and cancer.

It is also likely that MetS has a role in autoimmune disorders.

MetS can be prevented, and can be reversed, by avoiding refined sugar, especially in soft drinks. And physical activity is also extremely important.

No, this won't magically cure all diseases. But it will help A LOT. This is extremely important information for all Americans, who believe they can rely on prescription drugs to keep them healthy.

Humira is not a good solution for autoimmune disorders. It may be necessary sometimes in severe cases where nothing else works, and the symptoms are disabling. Try not to rely on it. Try the lifestyle suggestions -- they won't harm you and will probably help at least to some extent.

By the way, I have psoriasis which used to be pretty severe.
 
Old 05-09-2018, 02:35 PM
 
5,644 posts, read 13,230,340 times
Reputation: 14170
Quote:
Originally Posted by Good4Nothin View Post
Drugs like Humira suppress the immune system, and that is how they reduce the symptoms of autoimmune disorders. Suppressing the immune system for long periods of time is not a good idea, because the immune system helps prevent infections, cancer, etc.

If autoimmune disorders are growing fast, it's probably related to the unnatural modern lifestyle.

I was writing about metabolic syndrome (MetS) in the psychology forum, because it is related to psychological disorders, and to psychiatric drugs, as well as to heart disease, cancer, diabetes, dementia, etc. MetS is probably also a factor in autoimmune disorders.

Recent research has been showing what some medical scientists have been saying for decades -- MetS can be caused by high consumption of refined sugar, along with physical inactivity. In other words, the typical American lifestyle.

We did not evolve to ingest sugar apart from natural food, such as fruit. When sugar is eaten separately, with no fiber, too much energy is rapidly made available to the cells. Insulin does its job of shoving glucose into the cells, but it's too much, and eventually the cells become insulin resistant, in self-defense.

Insulin resistance of the cells in turn causes insulin production to increase.

High insulin levels in the blood are damaging, possibly contributing to artery disease.

And the mitochondria within each cell become overwhelmed by too much glucose. The lack of physical activity means most of the glucose is not being used for muscle contractions.

All this eventually leads to chronic inflammation. Chronic inflammation is the foundation of many of the current chronic and/or fatal diseases, such as type 2 diabetes, artery disease, Alzheimer's disease, and cancer.

It is also likely that MetS has a role in autoimmune disorders.

MetS can be prevented, and can be reversed, by avoiding refined sugar, especially in soft drinks. And physical activity is also extremely important.

No, this won't magically cure all diseases. But it will help A LOT. This is extremely important information for all Americans, who believe they can rely on prescription drugs to keep them healthy.

Humira is not a good solution for autoimmune disorders. It may be necessary sometimes in severe cases where nothing else works, and the symptoms are disabling. Try not to rely on it. Try the lifestyle suggestions -- they won't harm you and will probably help at least to some extent.

By the way, I have psoriasis which used to be pretty severe.
Ignoring for the moment the question of whether or not "Metabolic Syndrome" actually exists...and it is in fact controversial...

Pretty much everything you wrote here is false...

Especially the part about "too much sugar leading to insulin resistance"

That is NOT how insulin resistance occurs and there is in fact NO direct link to sugar consumption and diabetes unless the excess sugar consumption leads to obesity...

Now eating a healthy diet, limiting refined sugars and regular exercise while trying to maintain close to ideal body weight is excellent advice for anyone....no doubt

But to state "Humira is not a good solution for autoimmune diseases" "only necessary for severe cases" is patently FALSE and not supported by any science or even pseudo science
 
Old 05-09-2018, 03:07 PM
 
8,226 posts, read 3,423,206 times
Reputation: 6094
Quote:
Originally Posted by bluedevilz View Post
Ignoring for the moment the question of whether or not "Metabolic Syndrome" actually exists...and it is in fact controversial...

Pretty much everything you wrote here is false...

Especially the part about "too much sugar leading to insulin resistance"

That is NOT how insulin resistance occurs and there is in fact NO direct link to sugar consumption and diabetes unless the excess sugar consumption leads to obesity...

Now eating a healthy diet, limiting refined sugars and regular exercise while trying to maintain close to ideal body weight is excellent advice for anyone....no doubt

But to state "Humira is not a good solution for autoimmune diseases" "only necessary for severe cases" is patently FALSE and not supported by any science or even pseudo science
So ... the reason pretty much everything I wrote is false is just because you say it's false?

And you think Humira is harmless and good for health?
 
Old 05-09-2018, 03:11 PM
 
8,226 posts, read 3,423,206 times
Reputation: 6094
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822166/

"There are epidemiological data, plausible mechanisms and clinical data from diet intervention studies that provide strong support for a direct causal/contributory role of sugar in the epidemics of metabolic disease"
 
Old 05-09-2018, 03:16 PM
 
8,226 posts, read 3,423,206 times
Reputation: 6094
Sugar-Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes Sugar-Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes | Diabetes Care

Sugar-sweetened drinks raise risk of diabetes, metabolic syndrome https://www.endocrine.org/news-room/...bolic-syndrome
 
Old 05-10-2018, 10:47 AM
 
1,183 posts, read 708,705 times
Reputation: 3240
Quote:
Originally Posted by SailCT View Post
Humira works pretty well. Have been on it several times but then lost it due to change in medical insurance. Just got on it again and do not ever want to NOT be on it again or another one as good. I do realize that auto-immune diseases are THE fastest growing area of illnesses in the U.S. WHY??? Seems like about half of all ads now on TV are for Humira or a competitor and they all cure like 3-4 different things not just Psoriasis.
Like Crohn's Disease, Rheumatoid Arthritus, others??? Amazing.
Autoimmune diseases were previously untreatable. After decades of research, some of the basic pathways in individual autoimmune diseases have been figured out which then led to research to find molecules that could intervene in the pathways which, after many billions spent and clinical testing, led to approved treatments. Then, not surprisingly, those treatments were advertised. That's why there are so many ads now for these medications versus say 20 yrs back.


Psoriasis has a very old history and was recognized centuries ago. Apart from coal tar and sea-salt/UV, treatments have been limited. Biologics which actually block the pathway have improved the quality of life of many sufferers amazingly. People 50 years back could only dream of the treatments currently available - an research is still ongoing.


The immune system is complex. Just like every other system in the body - it can go wrong. What is more amazing is that it doesn't identify harmless things as pathogens or dangerous (or fail to distinguish self from non-self) more often than it actually does. Its pretty darn cool.

Last edited by Chint; 05-10-2018 at 11:01 AM..
 
Old 05-10-2018, 10:55 AM
 
1,183 posts, read 708,705 times
Reputation: 3240
Oh I see the medical genius Good4nothin is dispensing biological omniscience again. Thank God.


You know autoimmune diseases existed since before sugar was even refined, let alone consumed in large amounts right? Whatever its role in exacerbating multi-factorial issues or comorbidities such as AI your sentence about Humira (which only treats AI diseases largely involving the TNFalpha pathway anyway) is pure cross-eyed badger spit. Humira doesn't pretend to be a treat-all for every possible autoimmune disease. That would be fantasy tripe - you know like saying stopping sugar will cure all disease processes occurring in the US or alkalinizing people will cure cancer or shark cartilage .. well you get the idea. Specious stuff that people love to swallow as profound knowledge then trot out as fact.
 
Old 05-10-2018, 11:03 AM
 
Location: Central IL
20,722 posts, read 16,377,752 times
Reputation: 50380
Quote:
Originally Posted by Chint View Post
Oh I see the medical genius Good4nothin is dispensing biological omniscience again. Thank God.


You know autoimmune diseases existed since before sugar was even refined, let alone consumed in large amounts right? Whatever its role in exacerbating multi-factorial issues or comorbidities such as AI your sentence about Humira (which only treats AI diseases largely involving the TNFalpha pathway anyway) is pure cross-eyed badger spit. Humira doesn't pretend to be a treat-all for every possible autoimmune disease. That would be fantasy tripe - you know like saying stopping sugar will cure all disease processes occurring in the US or alkalinizing people will cure cancer or shark cartilage .. well you get the idea. Specious stuff that people love to swallow as profound knowledge then trot out as fact.
...ya know, when all you have is a hammer, EVERYTHING looks like a nail - psoriasis, psych issues, you name it.
 
Old 05-10-2018, 11:26 AM
 
8,226 posts, read 3,423,206 times
Reputation: 6094
Quote:
Originally Posted by Chint View Post
Oh I see the medical genius Good4nothin is dispensing biological omniscience again. Thank God.


You know autoimmune diseases existed since before sugar was even refined, let alone consumed in large amounts right?
Nowhere near the rates we have now. It has to be something in the modern environment. Do you really think that in previous times most people were sick, like they are now?

Yeah, I know you will say yes they were. And I will say no they weren't.

Our society is a gigantic health care disaster. Yes, people always got sick and died, there was no time of perfect health. People got sick and died because of unsanitary conditions in cities, and infections, things that are mostly taken care of today.

We can't go back a couple hundred years to a clean environment and see if they were healthy or not. But we do know of studies of people with traditional non-industrialized lifestyles, and according to the ones I have read, they are MUCH healthier than we are.
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