Applying to a different city in the same state (companies, cities, hours)

[NCguy980]

Are there any rules for applying to a different city but in the same state? Do companies filter you out if you're not in the same city or is it just by state? The cities I want to apply are 2-3 hours away from me.

[CapsChick]

State in your cover letter that you plan to relocate to their city on x date.