On threads that exceed 10 pages, I usually at least make an effort to read the OP's post and the last few pages. Sometimes, though, when it's obvious the thread has been completely derailed, I will just reply to the OP's post and ignore where the thread has gone. (I.e. if a thread about pretty much any topic ends up being about religion, which happens a lot on CD, I will reply to the original topic and ignore the last 5 pages that have turned into The Latest Atheism-Christian Debate.)